Meleuz, Ufa, Russian Federation
Meleuz, Ufa, Russian Federation
Samara, Russian Federation
Meleuz, Ufa, Russian Federation
The purpose of research is to develop techniques for chemical implementation of the obtained low molecular weight products with covalently bound iodine in the biodegradable matrix (glycyrrhizic acid) with obtaining nanosized composites, capable of metered cleavage of iodine in vivo. One of the vital trace elements is iodine. Adding iodine to food components is an advanced technology and it promotes replenishment of iodine deficiency in human organism. The most interesting compounds wherethe inorganic iodine are chemically bound to the organic matrix. The processes of formation of the complex "o-iodobenzoic acid-β-glycyrrhizic acid" and encapsulation mechanisms of 5-iodo-6-metiluratsila in nanoscale biodegradable matrix -β-glycyrrhizic acid by using physical and chemical methods of analysis – IR, UV and NMR spectroscopy. The evaluationof nano-sized ofsynthesized iodinebioorganic complexes by laser nanostructured analysis is carried out. The processes of deiodination o-iodobenzoic acid in vivo by high-performance liquid chromatography is examed. The conducted research showsthe bioavailability of synthesized nanostructured iodine organic-mineral complex.
iodine deficiency, NMR-, IR-, UV-spectroscopy, nano-sized, chromatography
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