THE PROTECTIVE INFLUENCE OF A MIXTURE OF ADAPTOGENIC PRODUCTS FROM HYPERICUM PERFORATUM AND RHODIOLA ROSEA ON WARM-BLOODED ORGANISM UNDER COLD AND HEAT STRESS

Ekaterina A. Litovchenko; Natalya V. Korshunova

doi:doi:10.12737/23257

THE PROTECTIVE INFLUENCE OF A MIXTURE OF ADAPTOGENIC PRODUCTS FROM HYPERICUM PERFORATUM AND RHODIOLA ROSEA ON WARM-BLOODED ORGANISM UNDER COLD AND HEAT STRESS

Published в Bulletin physiology and pathology of respiration · Volume 1, Issue 62, 2016 · Pages 81–84 · Rubrics: ORIGINAL RESEARCH

DOI 10.12737/23257

Received: 08.12.2016 Accepted: 15.12.2016 Published: 15.12.2016 Language of publication: RUS

Authors

Ekaterina A. Litovchenko ¹ · Natalya V. Korshunova ²

1 Amur State Medical Academy (Department of General Hygiene, Postgraduate student)
Blagoveschensk, Blagoveshchensk, Russian Federation

2 Amur State Medical Academy (Department of General Hygiene, Professor, Head of Department)
Blagoveschensk, Blagoveshchensk, Russian Federation

ABSTRACT

In the experimental conditions the possibility of increasing the resistance of rats to physical influence in the conditions of the use of a mixture of adaptogenic products (Hypericum perforatum and Rhodiola rosea) under cold and heat stress was studied. The animals were divided into 9 groups, each of them had 10 rats: the 1st group had intact animals which were held in standard conditions of vivarium; the 2nd group was the control group in which rats were exposed to cold during three hours daily (-15ºC, 50% humidity); the 3rd was the control group in which rats were exposed to heat during 45 minutes daily (+40ºC, 50% humidity); the 4th, 6th, 8th groups were the experimental groups in which before cooling animals had a daily intake of powder mixture of Hypericum perforatum and Rhodiola rosea in a dose of 30 mg/kg, 150 mg/kg, 300 mg/kg, respectively; the 5th, 7th, 9th groups were the experimental groups in which rats before being put in the heat climatic chamber were given a daily intake of powder mixture of Hypericum perforatum and Rhodiola rosea in a dose of 30 mg/kg, 150 mg/kg, 300 mg/kg, respectively. It was found out that cold and heat exposure reduces the resistance of experimental animals (in different degrees) to swimming in all the days of the experiment. Thus the length of swimming of intact animals was 146±3.4 min; whereas in animals under cold exposure in the control group it was 108±5.6 min, and under the exposure to heat it was 105±3.4 min (p<0.01). The introduction of a mixture of Hypericum perforatum and Rhodiola rosea into the food of animals, exposed to temperature effects in a dose of 150-300 mg/kg increased swimming time under exposure to cold up to 178±4.7 min (р<0.05) and under exposure to heat up to 181±3.0 min (р<0.05). At the 14th day the average duration of swimming of rats which took the mixture at a dose of 150-300 mg/kg against exposure to cold and heat was 192±3.0 min and 188±5.9 min, respectively. A similar trend was observed till the 28th day of research. Thus, the use of a mixture of Hypericum perforatum and Rhodiola rosea in conditions of prolonged heat and cold stress on the organism of experimental animals leads to significant increase in the resistance of rats to fatigue.

KEYWORDS

adaptogens cold stress heat stress resistance of organism fatigue physical performance.

Information References

Authors:

1. Amur State Medical Academy (Department of General Hygiene, Postgraduate student)

Blagoveschensk, Blagoveshchensk, Russian Federation

2. Amur State Medical Academy (Department of General Hygiene, Professor, Head of Department)

Blagoveschensk, Blagoveshchensk, Russian Federation

Type:

Article

Pages:

from 81 to 84

Status:

Published

Language:

Russian

Keywords:

adaptogens, cold stress, heat stress, resistance of organism, fatigue, physical performance.

References

1. Borisova I.G., Seĭfulla R.D., Zhuravlev A.I. The effect of antioxidants on physical work capacity and lipid peroxidation in the body. Farmakologiya i toksikologiya 1990; 4:89-92 (in Russian).

2. Galenok V.A., Dikkert V.E. Hypoxia and carbohydrate metabolism. Novosibirsk: Nauka; 1985 (in Russian).

3. Dorovskikh V.A., Voronin N.I., Korshunova N.V. Cold. Adaptation. Correction changes. Blagoveshchensk; 1998 (in Russian).

4. Kozyreva T.V. Adaptive changes in temperature sensitivity in humans under the conditions of cold, heat, and prolonged exercise. Fiziologiya cheloveka 2006; 32(6):103-108 (in Russian).

5. Korshunova N.V. Toxicological-hygienic substantiation of use of products of processing of antlers to increase the resistance of the organism to cold: PhD (DSc) thesis. St. Petersburg; 2001 (in Russian).

6. Meerson F.Z., Pshennikova M.G. Adaptation to stress situations and physical loads. Moscow: Meditsina; 1988 (in Russian).

7. Pavlov A.S., Pavlova T.V. Morphological and physiological indicators of thermal adaptation. Fiziologiya cheloveka 1992; 18(2):108-113 (in Russian).

8. Panin L.E., Kuzmenko D.I. Role of nutrition in changes in energy metabolism in stress. Voprosy pitaniya 1982; 3:15-18 (in Russian).

Доступ и загрузка

🗂 JATS XML ❝ To cite 📎 Citations

—

Views

—

Downloads

Citations

Индексируется в

THE PROTECTIVE INFLUENCE OF A MIXTURE OF ADAPTOGENIC PRODUCTS FROM HYPERICUM PERFORATUM AND RHODIOLA ROSEA ON WARM-BLOODED ORGANISM UNDER COLD AND HEAT STRESS

Confirmation

Регистрация