ANTIBIOTIC RESISTANCE OF MICROORGANISMS ISOLATED FROM PATIENTS OF SURGICAL HOSPITAL
Abstract and keywords
Abstract (English):
Infections received in the course of healthcare delivery continue to be an urgent medical and socio-economical issue. This problem is exacerbated by formation and wide spread of strains polyresistant to current germicides.The article presents the results of a study of antibiotic resistance of microorganisms isolated from patients of surgical hospitalof Neryungri Central Regional Hospital. Microorganisms were resistant to various antimicrobial drugs. E.coli were resistant to ampicillinum, ampicillinum/sulbactam and ceftriaxonum; Klebsiellaspp. – to ampisiillinum, chlo-ramphenicolum and cefotaxime; Pseudomonas aeruginosa – to ciprofloxacinum and gentamicinum, Acinetobacterspp. – gentamicinum, ceftazidime and ceftriaxonum; Staphylococcus – to penicillinum. Escherichia coli and Klebsiella spp. produced extended spectrum beta-lactamases (ESBL). Among E.coli, Pseudomonas aeruginosa and Acinetobacter spp. were identified strains resistant to carbapenems. MRSA and MRSE were identified.

Keywords:
infections associated with medical care, surgical hospital, antibiotic resistance of microorganisms
References

1. AnganоvaEV, MamontovaLM, IvanovaNG, IlarovaVI (2003). Antibiotic resistance of microorganisms isolated from hospitalized patients in different territories [Anti-biotikorezistentnost’ mikroorganizmov, vydelennykh ot gospitalizirovannykh bol’nykh na razlichnykh territori-yakh].Bulleten’ Vostocno-Sibirskogo naucnogo centra, (3), 105-110

2. BrusinаEB, RychagovIP (2007).Epidemiological significance of hospital infections in surgery and the role of different sources of infection [Epidemiologicheskoe znachenie vnutribol’nichnykh infektsiy v khirurgii i rol’ razlichnykh istochnikov infektsii]. Glavnaya meditsinskaya sestra, (9), 97-102

3. BrikoNI, BrusinaEB, ZuevaLP (2013). Hospital strain – the unknown reality[Gospital’nyy shtamm – nepoznan-naya real’nost’]. Epidemiologiya i vaktsinoprofilaktika, (1), 30-33

4. GudkovaEI, AdarchenkoAA, SlabkoIN, Lastochki-naTM (2003).Microbiological monitoring of hospital ekovars of conditionally pathogenic bacteria –causa-tive agents of hospital infections [Mikrobiologicheskiy monitoring gospital’nykh ekovarov uslovno-patogennykh bakteriy – vozbuditeley vnutribol’nichnykh infektsiy]. Meditsinskie novosti, (3), 11-15.

5. ZuevaLP (2007).Epidemiological diagnostics – the basis of the system of prevention of hospital infections [Epidemiologicheskaya diagnostika – osnova sistemy profilaktiki vnutribol’nichnykh infektsiy]. Epidemiologiya i vaktsinoprofilaktika, (1), 12-16.

6. KozyrevaVK, EdelsteinMV, TapalskyDV, AzizovIS(2012). Clonal spread of CTX-M-5-producing of nosoco-mial strains of Salmonella typhimurium in Russia, Belarus and Kazakhstan [Klonal’noe rasprostranenie STKh-M-5-produtsiruyushchikh nozokomial’nykh shtammov Sal-monella typhimurium v Rossii, Belorusi i Kazakhstane].Klinicheskaya mikrobiologiya i antimikrobnaya khimiotera-piya, 14(1), 38-50.

7. KozlovRA, GolubAV (2011). The strategy of using antimicrobial drugs as an attempt to renaissance of antibiotics [Strategiya ispol’zovaniya antimikrobnykh preparatov kak popytka renessansa antibiotikov]. Klinich -eskaya mikrobiologiya i antimikrobnaya khimioterapiya, 13(4), 322-334

8. KuznetsovaMV, KarpuninaTI, YegorovaDO (2010).Carbapenem-resistant strains of Pseudomonas aeruginosain hospitals of the city of Perm [Karbapenemoustoychivye shtammy Pseudomonas aeruginosa v statsionarakh goroda Perm’]. Klinicheskaya mikrobiologiya i antimikrobnaya khimioterapiya, 12(3), 246-252.

9. KryukovaNF, AdamovichSN, MirskovaAM, Angano-vaEV (2012).Stimulators of Staphylococcus growth for the accelerated diagnostics of infections associated with health care [Stimulyatory rosta stafilokokka dlya uskore-nnoy diagnostiki infektsiy, svyazannykh s okazaniem meditsinskoy pomoshchi].Bulleten’ Vostocno-Sibirskogo naucnogo centra, (5), 239-242.

10. Determination of sensitivity of microorganisms to antibiotics: methodical instructions N4.2.1890-04. (1980). [Opredelenie chuvstvitel’nosti mikroorganizmov k antibakterial’nym preparatam: Metodicheskie ukazaniya Federal’nogo centra Gossanjepidnadzora Minzdrava Rossii N4.2.1890-04], 91.

11. .About unification of microbiological (bacteriological) methods of research used in clinical diagnostic labo-ratories of medical-diagnostic institutions (1985). [Ob unifikatsii mikrobiologicheskikh (bakteriologicheskikh) metodov issledovaniya, primenyaemykh v kliniko-diag-nosticheskikh laboratoriyakh lechebno-diagnosticheskikh uchrezhdeniy]. Prikaz ministerstva zdravoohraneniya SSSR No 535 ot 22.04.85.

12. PlekhanovVN (2013).Clinical and microbiological characteristics of stationary infections of urinary tract in people of working age in the North [Kliniko-mikrobi-ologicheskaya kharakteristika statsionarnykh infektsiy mochevyvodyashchikh putey u lits trudosposobnogo voz-rasta v usloviyakh Severa].Bulleten’ Vostocno-Sibirskogo naucnogo centra, (11), 64-68.

13. SavilovED, AstafjevVA, ZhdanovaSN, ZarudnevEA (2011). Epidemiological analysis: Methods of statistical processing of the material [Epidemiologicheskiy analiz: Metody statisticheskoy obrabotki materiala], 156.

14. ShkarinVV, KovalishenaOV (2009). The concept of multi-level system of epidemiological surveillance of hospital infections [Kontseptsiya mnogourovnevoy sistemy epidemiologicheskogo nadzora za gospital’nymi infektsiyami]. Meditsinskiy al’manakh, (2), 14-21.

15. YakovlevSV (2011). Rationale for antibiotic therapy of nosocomial infections caused by multiresistant microorganisms [Obosnovanie antibakterial’noy terapii nozokomial’nykh infektsiy, vyzvannykh polirezistentnymi mikroorganizmami]. Klinicheskaya farmakologiya i terapiya, 20(2), 24-34

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