CLEARANCE OF CARBONYL-MODIFIED LIPOPROTEINS FROM THE BLOODSTREAM OF RABBITS

Maria Grechnikova; Sergey Domogatskiy; Galina Konovalova; Alla Tikhaze; Vadim Lankin

doi:doi:10.12737/article_590823a4b59f98.13160142

UDC 61

CLEARANCE OF CARBONYL-MODIFIED LIPOPROTEINS FROM THE BLOODSTREAM OF RABBITS

Published в Acta biomedica scientifica · Volume 1, Issue 3, p. 2, 2017 · Pages 104–108 · Rubrics: Experimental Study in biology and medicine

DOI 10.12737/article_590823a4b59f98.13160142

Received: 27.04.2017 Accepted: 02.05.2017 Published: 02.05.2017

Authors

Maria Grechnikova ¹ · Sergey Domogatskiy ² · Galina Konovalova ³ · Alla Tikhaze ⁴ · Vadim Lankin ⁵

1 Russian Cardiology Research and Production Complex (laborant-issledovatel')
Moskv, Moscow, Russian Federation

2 Russian Cardiology Research and Production Complex (zaveduyuschiy laboratoriey)
Moskva, Moscow, Russian Federation

3 Russian Cardiology Research and Production Complex (starshiy nauchnyy sotrudnik)
Moskva, Moscow, Russian Federation

4 Institute of Clinical Cardiology (laboratoriya biohimii svobodnoradikal'nyh processov, veduschiy nauchnyy sotrudnik)
Moskva, Moscow, Russian Federation

5 E.I. Chazov National Medical Research Centre of Cardiology (otdel biohimii svobodnoradikal'nyh processov)
Moscow, Moscow, Russian Federation

ABSTRACT

Issledovali klirens al'degid-modificirovannyh lipoproteidov nizkoy plotnosti (LNP) u krolikov s ispol'zovaniem izolirovannyh pri pomoschi preparativnogo ul'tracentrifugirovaniya biotinilirovannyh LNP krolikov i FITC-mechenyh LNP cheloveka. Glioksal'- i metilglioksal'-modificirovannye LNP krolikov i cheloveka cirkuliruyut v krovotoke takoe zhe vremya, chto i nativnye LNP. MDA-modificirovannye LNP bystro eliminiruyutsya iz krovotoka. Veroyatno, glioksal'- i metilglioksal'-modificirovannye LNP bolee aterogenny, v to vremya kak MDA-modificirovannye LNP mogut podvergat'sya usilennoy utilizacii.

KEYWORDS

okislitel'nyy stress modificirovannye lipoproteidy nizkoy plotnosti malonovyy dial'degid glioksal' metilglioksal' ateroskleroz saharnyy diabet

Information Text References

Authors:

1. Russian Cardiology Research and Production Complex (laborant-issledovatel')

Moskv, Moscow, Russian Federation

2. Russian Cardiology Research and Production Complex (zaveduyuschiy laboratoriey)

Moskva, Moscow, Russian Federation

3. Russian Cardiology Research and Production Complex (starshiy nauchnyy sotrudnik)

Moskva, Moscow, Russian Federation

4. Institute of Clinical Cardiology (laboratoriya biohimii svobodnoradikal'nyh processov, veduschiy nauchnyy sotrudnik)

Moskva, Moscow, Russian Federation

5. E.I. Chazov National Medical Research Centre of Cardiology (otdel biohimii svobodnoradikal'nyh processov)

Moscow, Moscow, Russian Federation

Type:

Article

Pages:

from 104 to 108

Status:

Published

Subject area:

UDC 61

Language:

Russian

Keywords:

okislitel'nyy stress, modificirovannye lipoproteidy nizkoy plotnosti, malonovyy dial'degid, glioksal', metilglioksal', ateroskleroz, saharnyy diabet

Text

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References

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