Irkutsk, Irkutsk region, Russian Federation
Irkutsk, Irkutsk region, Russian Federation
Irkutsk, Irkutsk region, Russian Federation
Issledovano soderzhanie produktov perekisnogo okisleniya lipidov (POL) i antiokislitel'naya aktivnost' (AOA) syvorotki krovi v usloviyah modelirovaniya hronicheskogo immobilizacionnogo stressa. Aktivaciya POL sopryazhena s tormozheniem skorosti vsasyvaniya glyukozy. Kursovoe vvedenie 2-etil-6-metil-3- oksipiridina sukcinata (EMOS) v doze 10 mg/kg privodilo k izmeneniyu soderzhaniya pervichnyh i konechnyh produktov POL i povysheniyu AOA syvorotki. Vvedenie EMOS pri immobilizacionnom stresse privodilo k uvelicheniyu skorosti vsasyvaniya glyukozy do pokazateley kontrol'noy gruppy.
stress, perekisnoe okislenie lipidov, 2-etil-6-metil-3-oksipiridina sukcinat, glyukoza, vsasyvanie
1. Voronina TA (2001). Mexidol antioxidant. The main psychoactive effects and the mechanism of its action [Antioksidant meksidol. Osnovnye psikhotropnye effekty i mekhanizm deystviya] Psikhofarmakologiya i biologicheskaya narkologiya, 1 (1), 2-12.
2. Gavrilov VB, Mishkorudnaya MI (1983). Spectrophotometric determination of lipid hydroperoxide content in blood plasma [Spektrofotometricheskoe opredelenie soderzhaniya gidroperekisey lipidov v plazme krovi]. Laboratornoe delo, (3), 33-36.
3. Gavrilov VB, Gavrilova AR, Mazhul LM (1987). The analysis of methods of determining products of lipid peroxidation in serum with the thiobarbituric acid test [Analiz metodov opredeleniya produktov perekisnogo okisleniya lipidov v syvorotke krovi po testu s tiobarbiturovoy kislotoy]. Voprosy meditsinskoy khimii, (1), 118-122.
4. Gromova LV, Gruzdkov AA (1993). The relative role of different mechanisms of glucose absorption in the small intestine under physiological conditions [Otnositel’naya rol’ razlichnykh mekhanizmov vsasyvaniya glyukozy v tonkoy kishke pri fiziologicheskikh usloviyakh]. Fiziologicheskiy zhurnal im. I.M. Sechenova, 79 (6), 65-72.
5. Kamyshnikov VS (2000). Clinical and biochemical laboratory diagnosis manual [Spravochnik po klinikobiokhimicheskoy laboratornoy diagnostike], (1), 496.
6. Klebanov GI, Babenkova IV, Teselkin YO (1988). Evaluation of blood plasma antioxidant activity with the use of egg yolk lipoproteins [Otsenka AOA plazmy krovi s primeneniem zheltochnykh lipoproteidov]. Laboratornoe delo, (5), 59-60.
7. Kolesnikova LI, Dolgikh VV, Prokhorova ZV, Grebyonkina LA, Vlasov BY, Iljin VP (2010). Features state of the system “lipid peroxidation – antioxidant protection” and of calcium metabolism in adolescents with essential hypertension [ Osobennosti sostoyaniya sistemy « perekisnogo okisleniya lipidov – antioksidantnoy zashchity» i obmena kal’tsiya u detey podrostkovogo vozrasta pri essentsial’noy gipertenzii]. Pediatriya, 89 (3), 10-14.
8. Korytov LI, Suslikova MI (2014). The modeling method of enteroenteroanastomosis in small laboratory animals: Patent N 2535411 of the Russian Federation [Sposob modelirovaniya enteroenteroanastomoza u melkikh laboratornykh zhivotnykh. Patent № 2535411 Ros. Federatsiya].
9. Maslova MN (2005). Molecular stress mechanisms [Molekulyarnye mekhanizmy stressa]. Rossiyskiy fiziologicheskiy zhurnal im. I.M. Sechenova, 91 (11), 1320-1328.
10. Mexidol in the treatment and experiment (2006) [Meksidol v klinike i eksperimente]. Byulleten’ eksperimental’noy biologii i meditsiny, (1), 252.
11. Sheptitskiy VA, Guska NI (1996). Ca2-dependent absorption of glucose in the small intestine of rats under antiorthostatic stress [Ca2-zavisimoe vsasyvanie glyukozy v tonkoy kishke krys pri antiortostaticheskom stresse]. Rossiyskiy fiziologicheskiy zhurnal im. I.M. Sechenova, (3), 125-131.
12. Sheptitskiy VA, Popanu LV, Cheban LN (2011). Physiologically-based approaches to the maintenance of digestive and transport functions of the small intestine in sanogenic limits under stress with nutritional factors [Fiziologicheski obosnovannye podkhody k podderzhaniyu pishchevaritel’no-transportnykh funktsiy tonkoy kishki v sanogennykh limitakh pri stresse s pomoshch’yu nutritivnykh faktorov]. Buletinul AŞM. Ştiinţelevieţii, 315 (3), 42-50.
13. Aikens J, Dix ТА (1991). Perhydroxyl radical (HOO.) initiated lipid peroxidation. The role of fatty acid hydroperoxides. Journal of Chemical Biology, 266 (23), 15091–15098.
14. Shepherd EJ, Helliwel PA, Mace OJ, Morgan EL, Patel N, Kellett GL (2004). Stress and glucocorticoid inhibit apical GLUT2-trafficking and intestinal glucose absorption in the rat small intestine. Journal of Physiology. (L.), 560 (1), 281-290.
