DIAGNOSTICS OF HELICOBACTER PYLORI INFECTION BY ENZYME IMMUNOASSAY IN PATIENTS WITH CALCULOUS CHOLECYSTITIS
Abstract and keywords
Abstract (English):
Zhelchnokamennaya bolezn' yavlyaetsya odnim iz naibolee chasto vstrechayuschihsya zabolevaniy organov pischeva- reniya. Vospalitel'nye izmeneniya v zhelchevyvodyaschih putyah otyagoschayut klinicheskoe techenie zhelchnoka- mennoy bolezni, kak v dooperacionnom, tak i v posleoperacionnom periode, a takzhe yavlyayutsya prichinoy vozniknoveniya striktur, deformaciy vnepechenochnyh zhelchnyh protokov v otdalennom periode. Odnim iz naibolee groznyh oslozhneniy zhelchnokamennoy bolezni yavlyaetsya ostryy kal'kuleznyy holecistit. Opredelenie soderzhaniya IgG k Helicobacter pylori v kompleksnoy diagnostike yavlyaetsya vazhnym u bol'nyh s kal'kuleznym holecistitom. Nami provedeno prospektivnoe issledovanie pacientov (n = 105) v vozraste ot 30 do 50 let, stradayuschih razlichnymi variantami kal'kuleznogo holecistita, v predoperacionnom i posleoperacionnom periode metodom immunofermentnogo analiza. Immunofermentnyy analiz yavlya- etsya dostovernym, dostupnym, naimenee invazivnym metodom diagnostiki helikobakternoy infekcii. Ustanovleno znachitel'noe uvelichenie IgG k Helicobacter pylori u bol'nyh s kal'kuleznym holecistitom do operativnogo vmeshatel'stva i posleduyuschee snizhenie na 10-e sutki posle holecistektomii. Diagno- stika inficirovaniya zhelchnogo puzyrya Helicobacter pylori povysit lechebnuyu effektivnost' i pozvolit vyrabotat' profilakticheskie meropriyatiya v preduprezhdenii oslozhneniy zhelchnokamennoy bolezni.

Keywords:
kal'kuleznyy holecistit, Helicobacter pylori, immunoglobulin, immunofermentnyy analiz, holecistektomiya
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References

1. Diagnostika Helicobacter pylori

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