graduate student from 01.09.2015 until now
Moskva, Russian Federation
employee
Ufa, Ufa, Russian Federation
Predmet. Sredi rasprostranennyh endokrinnyh patologiy v poslednie desyatiletiya na pervom meste stoit saharnyy diabet. Po dannym Vsemirnoy organizacii zdravoohraneniya, k 2030 godu v mire kolichestvo bol'nyh saharnym diabetom uvelichitsya do 366 mln chelovek. Giperglikemiya uvelichivaet rasprostranennost' vospalitel'nyh zabolevaniy slizistoy obolochki rta, vospalitel'nyh izmeneniy parodonta, utyazhelyaya techenie processa i snizhaya kachestvo lecheniya. V dannoy stat'e rassmatrivaetsya vliyanie vospalitel'nyh zabolevaniy slizistoy obolochki rta i glikemicheskogo kontrolya na urovni IL-1B v desnevoy zhidkosti u pacientov s saharnym diabetom 1 tipa. Cel'. Izuchenie vliyaniya tyazhesti vospalitel'nyh zabolevaniy slizistoy obolochki rta i glikemicheskogo kontrolya na urovni IL-1B v desnevoy zhidkosti u pacientov s saharnym diabetom 1 tipa. Metodologiya. V processe issledovaniya byli provedeny zabor plazmy krovi dlya opredeleniya urovney glikirovannogo gemoglobina, sobrany obrazcy desnevoy zhidkosti dlya opredeleniya urovney IL-1B u pacientov s saharnym diabetom 1 tipa, imeyuschih razlichnye zabolevaniya slizistoy obolochki rta. Rezul'taty. V rezul'tate provedennogo nami issledovaniya pokazano znachitel'noe uvelichenie urovney vospalitel'nogo mediatora IL-1B v desnevoy zhidkosti u pacientov s insulinozavisimym saharnym diabetom s zabolevaniyami slizistoy obolochki rta i yavleniyami hronicheskogo parodontita. Vyvody. Nashe issledovanie demonstriruet, chto giperglikemiya vliyaet na povyshenie urovnya vospalitel'nogo mediatora IL-1B v desnevoy zhidkosti, chto privodit k povysheniyu chastoty i tyazhesti vospalitel'nyh zabolevaniy slizistoy obolochki rta i vospalitel'nyh izmeneniy parodonta u pacientov s saharnym diabetom 1 tipa.
saharnyy diabet 1 tipa, interleykin-1b, zabolevaniya slizistoy obolochki rta, giperglikemiya
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10. Cutler C.W., Machen R.L., Jotwani R., Iacopino A.M. Heightened gingival inflammation and attachment loss in diabetics with hyperlipidemia. J. Periodontol, 2014, vol. 70, pp. 1313‑1321.
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12. Salvi G.E., Yalda B., Collins J.G. et al. Inflammatory mediator response as a potential risk marker for periodontal diseases in insulindependent diabetes mellitus patients. J Periodontol, 2012, vol. 68, pp. 127‑135.
