, Russian Federation
, Russian Federation
, Russian Federation
, Russian Federation
, Russian Federation
For the first time, a detailed study of the chemical composition of ethanol extract of dried marsh (swamp), a product obtained after preliminary exhaustive last ex-traction with n-hexane, toluene, chloroform and acetone was performed. Chromatography-mass spectrometry made it possible to identify 119 individual compounds in this extract with the determination of their quantitative content, mass spectra and structural formulas, and the calculation of the structural-group composition was performed. A characteristic feature of the extract is the presence of significant amounts of nitrogen and sulfur-containing compounds (20.04), esters (21.47), sterols (18.54), carboxylic acids (8.15) and hydrocarbons (7.15) (wt. % of the extract). In addition, the extract contains phenols, ketones, aldehydes, alcohols and glycosides: 5.01; 4.34; 4.88; 3.16 and 3.12 (wt. % of the extract), respectively. Dominance in the extract of nitrogen-sulfur-containing and compounds; environment of sterols-betulin and its derivatives, esters, as well as the presence of different structure of phenols, glycosides, aldehydes and alcohols makes it possible to assume a wide range of pharmacological activity of drugs based on ethanol extract of dried marsh (marsh).
marsh marsh, chromatography-mass spectrometry
1. Nikonov G.K., Manuylov B.M. Osnovy sovremennoy fitoterapii. OAO Izdatel'stvo «Medicina», 2005, 520 s.
2. Vinogradov T.A., Gazhev B.N. Prakticheskaya fitoterapiya. Seriya «Polnaya enciklopediya». M.: «OLMA-PRESS»; SPb.: Izdatel'skiy dom «Neva», «Veleri SPD», 1998. 640 s.
3. Popov A.P. Lekarstvennye rasteniya v narodnoy medicine. – Kiev: Zdorov'e, 1970. – 313 s.
4. Nikolashkin A.N., Selezenev N.G., Popov D.M., Potanina O.G. Razrabotka farmakopeynoy stat'i "sushenica topyanaya trava" dlya gosudarstvennoy farmakopei xii izdaniya. V sbornike: Materialy nauchnoy konferencii universiteta posvyaschennoy 60-letiyu so dnya osnovaniya Ryazanskogo gosudarstvennogo medicinskogo universiteta imeni akademika I.P. Pavlova na Ryazanskoy zemle. Ryazanskiy gosudarstvennyy medicinskiy universitet imeni akademika I.P. Pavlova. 2010. S. 293-296.
5. Nikolaeva I.G., Nikolaeva G.G. Mikroelementnyy sostav sushenicy topyanoy // Sibirskiy medicinskiy zhurnal (Irkutsk). 2005. T. 55. № 6. S. 64-65.
6. Nadtochiy I.N., Budrevskaya I.A. Areal i zona vredonosnosti sushenicy topyanoy (bolotnoy) gnaphalium uliginosum l. (filafinella uliginosa (l.) opiz.) (semeystvo astrovye asteraceae dumort.) // Vestnik zaschity rasteniy. 2008. № 4. S. 65.
7. Nikolashkin A.N., Potanina O.G., Popov D.M., Selezenev N.G. Sovershenstvovanie standartizacii travy sushenicy topyanoy // Farmaciya. 2010. № 2. S. 12-14.
8. Nikolashkin A.N., Selezenev N.G., Popov D.M. Razrabotka I Tehnologicheskiy Analiz Nastoyki Sushenicy Topyanoy // Zhurnal nauchnyh statey Zdorov'e i obrazovanie v XXI veke. 2017. T. 19. № 11. S. 245-249.
9. Hadarcev A.A., Suhih G.T., Platonov V.V., Dunaev V.A., Yarkova T.A. Himicheskiy sostav organicheskogo veschestva sushenicy topyanoy (bolotnoy) (gnafalium uliginosum l., semeystvo astrovye - asteraceae) // Vestnik novyh medicinskih tehnologiy. 2019. T. 26. № 1. S. 82-88.