employee
Stavropol', Stavropol, Russian Federation
employee
Stavropol', Stavropol, Russian Federation
employee
Stavropol', Stavropol, Russian Federation
graduate student
Stavropol', Stavropol, Russian Federation
employee
Stavropol', Stavropol, Russian Federation
student
Stavropol', Stavropol, Russian Federation
student
Stavropol', Stavropol, Russian Federation
Importance. Despite the improvement of diagnostic methods and the introduction of new technologies in the treatment of pathology of the oral mucosa, it is difficult to achieve stable remission, since 70 % of cases are based on somatic and bodily suffering factors. The article presents data from a comparative analysis of the use of the traditional treatment regimen for patients with pathology of the oral cavity and the inclusion of the latest generation of antipsychotics in the treatment regimen. It was established that, when applied, a tendency towards normalization of psychological and autonomic status was observed. The inclusion of anxiolytics and antioxidants in the complex of general therapy for patients with pathology of the oral mucosa contributed to a more pronounced positive dynamics of achieving and prolonging the phase of remission. Objectives — to evaluate the effectiveness of introducing drugs of the latest generation of antipsychotics into the traditional treatment regimen for patients with pathology of the oral cavity. Methodology. Under our supervision, there were 30 patients aged 40 to 60 years with a diagnosis of pathology of the oral mucosa and pathology of the periodontium. All examined were divided into 2 groups: the main (15 people) and control (15 people). Results. Clinical well-being, manifested in a subjective decrease in pain in the tongue, feelings of rawness, tingling, numbness, awkwardness, in the tongue, was noted already at the 5th visit in 67 % of patients of the main group, while in the control group in 17 % of patients. Conclusions. The inclusion of anxiolytics and antioxidants in the complex of general therapy for patients with pathology of the oral mucosa contributed to a more pronounced positive dynamics of achieving and prolonging the phase of remission. Our data allow us to implement this treatment regimen in practical healthcare.
nosogenic depression, fear, oral mucosa, pain, anxiolytic
1. Mordasov, N. A., Ivanyuta, I. V., Eremenko, A. V., Kuznetsova, O. V. (2016). Otsenka rezul'tatov kompleksnoy terapii khronicheskogo steroidnogo generalizovannogo [Evaluation of the results of complex therapy of chronic steroid generalized]. Aktual'nyye voprosy klinicheskoy stomatologii : sbornik nauchnykh rabot [Collection of Topical Issues in Clinical Dentistry : collection of scientific works], 109–112. (In Russ.)
2. Mordasov, N. A., Novikov, S. V., Kasimova, G. V., Ivanyuta, I. V. (2017). O roli i metodakh vozdeystviya na mikrotsirkulyatornyye narusheniya pri zabolevaniyakh parodontal'nogo kompleksa [On the role and methods of influence on microcirculatory disorders in diseases of the periodontal complex]. Aktual'nyye aspekty sovremennoy stomatologii i implantologii : materialy nauchno-prakticheskoy konferentsii [Collection of Actual Aspects of Modern Dentistry and Implantology : materials of the scientific-practical conference], 75–77. (In Russ.)
3. Elovikova, T. M., Karaseva, V. V., Ermishina, E. Yu., Shimova, M. E., Skurikhina, Y. S. (2019). Opyt provedeniya professional'noy gigiyeny polosti rta u patsiyentov s khronicheskim parodontitom v sochetanii s medikamentozno assotsiirovannym osteonekrozom chelyusti [Experience in professional oral hygiene in patients with chronic periodontitis in combination with drug-associated jaw osteonecrosis]. Problemy stomatologii [Problems of dentistry], 3, 28–33. DOI: https://doi.org/10.18481/2077-7566-2019-15-3-28-33 (In Russ.)
4. Solovieva, O. A., Karakov, K. G., Khachaturian, E. H. E., Savelyev, P. A., Sarkisov, A. A. (2016). Protivovospalitel'naya i antimikrobnaya terapiya pri lechenii verkhushechnykh periodontitov [Anti-inflammatory and antimicrobial therapy in the treatment of apical periodontitis]. Vestnik Meditsinskogo stomatologicheskogo instituta [Bulletin of the Medical Dental Institute], 1, 8–10. (In Russ.)
5. Lavrinenko, V. I., Saveliev, P. A. (2016). Ispol'zovaniye immunomodulyatorov pri lechenii vospalitel'no-destruktivnykh zabolevaniy parodonta [The use of immunomodulators in the treatment of inflammatory and destructive periodontal diseases]. NOVOYe V TEORII I PRAKTIKE STOMATOLOGII : materialy XV Foruma uchonykh Yuga Rossii v ramkakh nauchnoy konferentsii [NEW IN THE THEORY AND PRACTICE OF DENTISTRY : materials of the XV Forum of Scientists of the South of Russia as part of a scientific conference], 93–96. (In Russ.)
6. Ron, G. I., Pomazkina, A. A. (2016). Klinicheskiĭ sluchaĭ razvitiya krasnogo ploskogo lishaya na slizistoĭ obolochke polosti rta u muzhchiny molodogo vozrasta, dlitel'no rabotayushchego s personal'nym komp'yuterom [A clinical case of the development of lichen planus on the oral mucosa of a young man working for a long time with a personal computer]. Problemy stomatologii [Problems of Dentistry], 2, 50–54. DOI: https://doi.org/10.18481/2077-7566-2016-12-2-50-54 (In Russ.)
7. Novikov, S. V., Saveliev, P. A., Eremenko, A. V. (2012). Ispol'zovaniye kompleksnogo gomeopaticheskogo preparata «Mukoza Kompozitum» pri khronicheskom retsidiviruyushchem aftoznom stomatite [The use of the complex homeopathic preparation "Mucosa Compositum" in chronic recurrent aphthous stomatitis]. Aktual'nyye voprosy klinicheskoy stomatologii : materialy XLVI nauchno-prakticheskoy konferentsii stomatologov Stavropol'skogo kraya [Actual issues of clinical dentistry : materials of the XLVI Scientific and Practical Conference of Dentists of the Stavropol Territory], Stavropol State Medical Academy, 223–224. (In Russ.)
8. Karakov, K. G., Khachaturian, E. H. E., Vlasova, T. N., Ohanyan, A. V., Khachaturian, A. E. (2016). K voprosu o lechenii khronicheskikh retsidiviruyushchikh treshin gor'kogo i ikh sochetaniya s eksfoliativnym kheylitom [On the question of the treatment of chronic recurrent bitter cracks and their combination with exfoliative cheilitis]. Vestnik Meditsinskogo stomatologicheskogo instituta [Bulletin of the Medical Dental Institute], 1, 23–25. (In Russ.)
9. Chuykin, S. V., Akmalova, G. M., Ron, G. I., Chernysheva, N. D., Khonina, T. G. (2016). Obosnovaniye primeneniya tsinkosoderzhashchikh preparatov v kompleksnom lechenii bol'nykh krasnym ploskim lishayem slizistoy obolochki rta [The rationale for the use of zinc-containing drugs in the complex treatment of patients with lichen planus of the oral mucosa]. Problemy stomatologii [Problems of Dentistry], 3, 40–45. DOI: https://doi.org/10.18481/2077-7566-2016-12-3-40-45 (In Russ.)
10. Soloviev, O. A., Eremenko, A. V., Hakobyan, G. A., Gobaeva, O. G., Kuznetsova, M. V. (2015). Reaktsiya sosudistoy sistemy parodonta v applikatsii preparatov rastitel'nogo proiskhozhdeniya, immobilizirovannogo na polisorbe [Periodontal vascular system reaction in the application of herbal preparations immobilized on polysorb]. AKTUAL'NYYe VOPROSY I PERSPEKTIVY RAZVITIYA MEDITSINY : sbornik nauchnykh trudov po itogam mezhdunarodnoy nauchno-prakticheskoy konferentsii [ACTUAL ISSUES AND PROSPECTS OF DEVELOPMENT OF MEDICINE : collection of scientific papers following the results of the international scientific-practical conference], 96–98. (In Russ.)
11. Bishop, K., Dammer, P. M. (1997). Comparison of stainless steel flexofiles and NiTi Flex nickel-titanium files when forming simulated channels. Int Endod J, 30, 25–34.
12. Thompson, S. A., Dammer, P. M. H. (1997). Ability to form rotating nickel-titanium instruments ProFile .04 with a series 29 cone in simulated channels: part 1. Int Endod J, 30, 1–7.
13. Thompson, S. A., Dammer, P. M. H. (2000). The ability to form Hero 642 nickel-titanium rotating instruments in simulated root canals : Part 1. Int Endod J, 33, 248–254.
14. Garip, J., Gundai, M. (2001). The use of computed tomography when comparing files nickel-titanium and stainless steel in the preparation of simulated curved channels. Int Endod J, 34, 452–457.
15. Schaefer, E., Lohmann, D. (2002). Efficiency of FlexMaster rotating nickel-titanium tools compared to stainless steel manual K-Flexofile: part 1. The ability to mold in simulated curved channels. Int Endod J, 35, 505–513.
16. Schaefer, E., Florek, H. (2003). Efficiency of K3 nickel-titanium rotating tools compared to stainless steel manual KFlexofile. Part 1. Formative ability in simulated curved channels. Int Endod J, 36, 199–207.
17. Grimm, W. D. et al. (2016). Svyazannyye s nervnym grebnem stvolovyye kletki oral'nogo proiskhozhdeniya in vitro i ispol'zuyemyye v modeli osteoporoza ovets dlya issledovaniya v svyazi s terapevticheskimi effektami regeneratsii al'veolyarnoy kosti [Neural crest stem cells of oral origin in vitro and used in a sheep osteoporosis model for research in connection with the therapeutic effects of alveolar bone regeneration]. Meditsinskiy vestnik Severnogo Kavkaza [Medical Bulletin of the North Caucasus], 11, 2, 192–196. (In Russ.)
18. Grimm, W. D. et al. (2015). Translyatsionnyye issledovaniya i terapevticheskiye primeneniya stvolovykh kletok nervnogo grebnya v regenerativnoy periodontologii [Translational research and therapeutic applications of neural crest stem cells in regenerative periodontology]. Tekushchiye otchety o zdorov'ye polosti rta [Oral health reports], 2, 4, 266–274. (In Russ.)
19. Zhidovinov, A. V. et al. (2016). Issledovaniye lokal'nykh adaptatsionnykh reaktsiy luchevoy terapii u bol'nykh s defektami chelyustno-litsevogo proteza so s"yemnymi [The study of local adaptive reactions of radiation therapy in patients with defects in the maxillofacial prosthesis with removable]. Mezhdunarodnyy zhurnal prikladnykh i fundamental'nykh issledovaniy [International Journal of Applied and Basic Research], 5, 20. (In Russ.)
20. Syrac, S. V. et al. (2015). Lecheniye i reabilitatsiya bol'nykh s subtotal'nymi defektami nizhney chelyusti [Treatment and rehabilitation of patients with subtotal defects of the lower jaw]. Nauchno-issledovatel'skiy zhurnal farmatsevticheskikh, biologicheskikh i khimicheskikh nauk [Scientific journal of pharmaceutical, biological and chemical sciences], 6, 6, 1803–1810. (In Russ.)
21. Shatskaya, N. V., Vlasova, T. N., Eremenko, A. V., Vanchenko, N. B., Kuznetsova, O. V. (2017). Klinicheskaya otsenka vliyaniya kompleksa protivovospalitel'nykh preparatov na sostoyaniye tkaney parodonta [Clinical evaluation of the effect of a complex of anti-inflammatory drugs on the condition of periodontal tissues]. Aktual'nyye voprosy klinicheskoy stomatologii [Actual issues of clinical dentistry], 155–157. (In Russ.)
22. Vanchenko, N. B., Soloviev, O. A., Magduev, K. M., Khachirova, A. R., Ibragimova, M. Yu. (2017). O tselesoobraznosti ispol'zovaniya immunostimuliruyushchego preparata pri lechenii khronicheskogo generalizovannogo parodontita sredney stepeni tyazhesti [On the feasibility of using an immunostimulating drug in the treatment of chronic generalized periodontitis of moderate severity]. Perspektivy razvitiya sovremennoy meditsiny : sbornik nauchnykh trudov po itogam mezhdunarodnoy nauchno-prakticheskoy konferentsii [Prospects for the development of modern medicine. collection of scientific papers following the results of the international scientific-practical conference], 57–58. (In Russ.)
23. Vanchenko, N. B., Garus, Y. N., Soloviev, O. A., Pivnev, A. V., Kharatokova, R. M. (2017). Klinicheskaya effektivnost' ftorsoderzhashchego preparata pri lechenii giperestezii [Clinical efficacy of a fluorine-containing drug in the treatment of hyperesthesia]. Problemy sovremennoy meditsiny: aktual'nyye problemy : sbornik nauchnykh trudov po itogam mezhdunarodnoy nauchno-prakticheskoy konferentsii [Problems of modern medicine: actual problems : collection of scientific papers following the results of the international scientific-practical conference], 76–77. (In Russ.)
24. Vanchenko, N. B., Solovieva, O. A., Aybazova, M. M., Zarieva, F. B., Slyusarev, A. R. (2017). Metod kompleksnogo terapevticheskogo effekta pri lechenii khronicheskogo generalizovannogo parodontita putem korrektsii immunnogo statusa [The method of complex therapeutic effect in the treatment of chronic generalized periodontitis by correction of the immune status]. Problemy sovremennoy meditsiny : aktual'nyye problemy : sbornik nauchnykh trudov po rezul'tatam mezhdunarodnoy nauchnoy i prakticheskoy konferentsii [Problems of modern medicine: actual problems : collection of scientific papers on the results of international scientific and practical conference], 79–80. (In Russ.)
25. Vanchenko, N. B., Karakov, K. G., Lavrinenko, V. I., Novikov, S. V., Saveliev, P. A. (2017). Psikhoterapevticheskiy effekt pri lechenii khronicheskogo generalizovannogo parodontita [Psychotherapeutic effect in the treatment of chronic generalized periodontitis]. Aktual'nyye voprosy klinicheskoy stomatologii [Actual issues of clinical dentistry], 88–90. (In Russ.)
