Evaluation of the Efficiency of Hirudotherapy in Preparing for Pregnancy of the Women with Alimentary-Constitutional Obesity

N.S. Omarov; A. Abakarova

doi:doi:10.12737/5907

Evaluation of the Efficiency of Hirudotherapy in Preparing for Pregnancy of the Women with Alimentary-Constitutional Obesity

Published в Journal of New Medical Technologies · Volume 21, Issue 3, 2014 · Pages 91–95 · Rubrics: Clinical Picture and Methods of Treatment. Functional and Instrumental Diagnostics. New Medicinal Forms

DOI 10.12737/5907

Received: 06.10.2014 Accepted: 06.10.2014 Published: 06.10.2014 Language of publication: RUS

Authors

N.S. Omarov · A. Abakarova

ABSTRACT

The purpose is to study the effect of hirudotherapy in period of preparing for pregnancy the women with obesity and high risk of developing preeclampsia, on the state of hemostasis and lipid metabolism. Materials and methods. The main group (n=127) was the women with alimentary-constitutional obesity and high risk of developing preeclampsia, received courses of hirudotherapy; the comparison group (n=120) was the women with alimentary-constitutional obesity and the control group (n=50) was somatically healthy women. Hirudotherapy is carried out in accordance with the recommendations of the RF Ministry of health. The study of the basic biochemical parameters and serum lipid spectrum of blood was carried out by standard methods before and during the treatment process, there has also been the main links of hemostasis – platelet, procoagulant and link inhibitors of blood clotting. Results. The efficiency of the preparing for pregnancy in the patients resulted in improvement of general state of women (subjective and objective), contributed to the normalization in the basic biochemical parameters and blood-clotting sequences. The anticoagulant effect of procedures, for example, is manifested in normalization of the parameters of activated partial thromboplastin time and their stability for more than 9 months after the main course of hirudotherapy. Hyperaggregation of platelets with collagen to treatment occurred in 69,3%, after hirudotherapy it declined in all cases to standard values. By the time of pregnancy patients with severe obesity remained in 2,2 times less. Lipid profiles improved relative to a comparison group: total cholesterol decreased by 10.4%, low density lipoproteins – by 34.5%, triglycerides – by 20.8%, atherogenesis coefficient lowering by 1.2 times. Conclusion. Hirudotherapy can be recommended to correct the rheological properties of blood and lipid metabolism, which found out in patients with obesity.

KEYWORDS

obesity hirudotherapy preparing foe pregnancy hypercoagulability lipid metabolism.

Information References

Authors:

Type:

Article

Pages:

from 91 to 95

Status:

Published

Language:

Russian

Keywords:

obesity, hirudotherapy, preparing foe pregnancy, hypercoagulability, lipid metabolism.

References

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