CHEMICAL COMPOSITION OF ORGANIC SUBSTANCE OF OAK BAR ORDINARY (EMERGENCY) (QUERCUS ROBUR L, BEECH FAMILY - FAGACCAC) (MESSAGE III - CHLOROFORM EXTRACT)

V. Platonov; Aleksandr Hadarcev; G. Suhih; V. Frankevich; M. Volochaeva; V. Dunaev

doi:doi:10.12737/2409-3750-2020-6-1-53-56

UDC 61

CHEMICAL COMPOSITION OF ORGANIC SUBSTANCE OF OAK BAR ORDINARY (EMERGENCY) (QUERCUS ROBUR L, BEECH FAMILY - FAGACCAC) (MESSAGE III - CHLOROFORM EXTRACT)

Published в Clinical Medicine and Pharmacology · Volume 6, Issue 1, 2020 · Pages 53–56 · Rubrics: reviews

DOI 10.12737/2409-3750-2020-6-1-53-56

Received: 18.06.2020 Accepted: 18.06.2020 Published: 18.06.2020

Authors

V. Platonov ¹ · Aleksandr Hadarcev ² · G. Suhih ³ · V. Frankevich ⁴ · M. Volochaeva ⁵ · V. Dunaev ⁶

1 OOO «Terraprominvest»,
Russian Federation

2 Tula State University (medicinskiy institut, Direktor)
Tula, Tula, Russian Federation

3 Nacional'nyy medicinskiy issledovatel'skiy centr akusherstva, ginekologii i perinatologii im. V.I.Kulakova
Russian Federation

4 Nacional'nyy medicinskiy issledovatel'skiy centr akusherstva, ginekologii i perinatologii im. V.I.Kulakova
Russian Federation

5 Nacional'nyy medicinskiy issledovatel'skiy centr akusherstva, ginekologii i perinatologii im. V.I.Kulakova
Russian Federation

6 Tula State University (medicinskiy institut)
Russian Federation

ABSTRACT

This report presents the results of chromatography-mass spectrometry of a chloroform extract obtained after preliminary sequential exhaustive extraction of the bark of ordinary oak (petiole) n-hexane and toluene. The purpose of the study is to significantly expand the range of compounds that determine the composition of the organic matter of the bark of ordinary oak (petiole). Materials and research methods. The dried raw material is ground to a powder in a porcelain laboratory mill, which is then subjected to exhaustive sequential extraction with n-hexane and toluene at boiling points. Then, the solid residue was dried to constant weight in a vacuum oven, and then extraction was carried out with chloroform at its boiling point. Extraction with chloroform was completed when the refractive index was reached equal to its initial value, after which chloroform was distilled off in a vacuum rotary evaporator to obtain a dark brown oily residue. Thus, we can conclude that the pharmacological effect of the chloroform extract of ordinary oak bark (petiolate) will be determined by the presence of significant amounts of sterols, hydrocarbons, which are dominated by arenes, alkenes and cycloalkanes, esters formed mainly by dicarboxylic acid (Oxalic acid).

KEYWORDS

oak bark toluene extract n-hexane chloroform chromatography-mass spectrometry.

Information References

Authors:

1. OOO «Terraprominvest»,

Russian Federation

2. Tula State University (medicinskiy institut, Direktor)

Tula, Tula, Russian Federation

3. Nacional'nyy medicinskiy issledovatel'skiy centr akusherstva, ginekologii i perinatologii im. V.I.Kulakova

Russian Federation

4. Nacional'nyy medicinskiy issledovatel'skiy centr akusherstva, ginekologii i perinatologii im. V.I.Kulakova

Russian Federation

5. Nacional'nyy medicinskiy issledovatel'skiy centr akusherstva, ginekologii i perinatologii im. V.I.Kulakova

Russian Federation

6. Tula State University (medicinskiy institut)

Russian Federation

Type:

Article

Pages:

from 53 to 56

Status:

Published

Subject area:

UDC 61

Language:

Russian

Keywords:

oak bark, toluene extract, n-hexane, chloroform, chromatography-mass spectrometry.

References

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3. Platonov V.V., Hadarcev A.A., Suhih G.T., Dunaev V.A., Volochaeva M.V. Himicheskiy sostav orga-nicheskogo veschestva kory duba obyknovennogo (chereshchatogo) - (Quercus Robur l., semeystvo bukovye - Fagaceae) (soobschenie I - H-geksanovyy ekstrakt) // Vestnik novyh medicinskih tehnologiy. Elektronnoe izdanie. 2020. №1. Publikaciya 3-6. URL: http://www.medtsu.tula.ru/VNMT/ Bulletin/E2020-1/3-6.pdf (data obrascheniya: 13.02.2020). DOI:https://doi.org/10.24411/2075-4094-2020-16605

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CHEMICAL COMPOSITION OF ORGANIC SUBSTANCE OF OAK BAR ORDINARY (EMERGENCY) (QUERCUS ROBUR L, BEECH FAMILY - FAGACCAC) (MESSAGE III - CHLOROFORM EXTRACT)

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