EVALUATION OF THE CLINICAL EFFECTIVENESS OF TOOTHPASTE CONTAINING GRAPEFRUIT EXTRACT AND LYSOTECH AND PROTELYSE LYSATES IN THE COMPLEX TREATMENT OF INFLAMMATORY PERIODONTAL DISEASES

Svetlana Tokmakova; Olga Bondarenko; Yuliya Lunitsyna

doi:doi:10.18481/2077-7566-20-16-4-58-63

VAK Russia 14.01.2014 UDC 61 CSCSTI 76.29 Russian Classification of Professions by Education 31.07.01 Russian Library and Bibliographic Classification 566 BISAC MED016020

EVALUATION OF THE CLINICAL EFFECTIVENESS OF TOOTHPASTE CONTAINING GRAPEFRUIT EXTRACT AND LYSOTECH AND PROTELYSE LYSATES IN THE COMPLEX TREATMENT OF INFLAMMATORY PERIODONTAL DISEASES

Published в Actual problems in dentistry · Volume 16, Issue 4, 2020 · Pages 58–63 · Rubrics: THERAPEUTIC DENTISTRY

DOI 10.18481/2077-7566-20-16-4-58-63

Received: 03.12.2020 Accepted: 10.12.2020 Published: 28.12.2020 Language of publication: RUS

Authors

Svetlana Tokmakova ¹ iD · Olga Bondarenko ² · Yuliya Lunitsyna ³

1 Altai State Medical University (kafedra terapevticheskoy stomatologii, zaveduyuschaya kafedroy, professor)
from 01.01.2002 to 01.01.2019 Barnaul, Barkaul, Russian Federation

2 Altai State Medical University (Department of Dental Dentistry, assistant professor)
from 01.01.2001 to 01.01.2019 Barnaul, Barkaul, Russian Federation

3 Altai State Medical University (Department of Dental Dentistry, assistant professor)
from 01.01.2015 to 01.01.2019 Barnaul, Barkaul, Russian Federation

ABSTRACT

The preventive direction in dentistry is the leading one today. Individual oral hygiene plays a significant role in preventing the development of inflammatory periodontal diseases. The use of therapeutic and prophylactic toothpastes containing natural components with antibacterial properties is promising. Among plant extracts, grapefruit extract has the most pronounced antimicrobial activity. LysoTech and ProteLyse lysates, which have antimicrobial and immunomodulatory effects, have long been used in dentistry in the form of tablets for resorption in the complex treatment of various diseases. Their introduction into toothpastes is also considered a promising direction for the prevention and treatment of oral pathology. The aim of our study was to clinically evaluate the effectiveness of therapeutic and prophylactic toothpaste, which contains grapefruit extract and LysoTech and ProteLyse lysates, in patients with inflammatory diseases of periodontal tissues. A clinical and laboratory comparative study of two therapeutic and prophylactic toothpastes was conducted. The composition of the samples was identical, except for two components: grapefruit extract and LysoTech and ProteLyse lysates. The study involved 60 volunteers who were divided into two groups depending on the toothpastes used. The purifying and anti-inflammatory effects of the samples were evaluated for one month. An in vitro laboratory study was also conducted to identify the antimicrobial properties of toothpastes. During the work, high clinical results were noted in a group of volunteers using toothpaste with grapefruit seed extract and bacterial lysates, which are expressed in a decrease in PMA and SBI indices, and an improvement in oral hygiene. According to a laboratory study, the toothpaste containing grapefruit extract and LysoTech and ProteLyse lysates has a more pronounced antimicrobial and antifungal effect, which indicates a high preventive and therapeutic potential of the test sample.

KEYWORDS

periodontal inflammatory diseases prevention toothpaste grapefruit extract LysoTech and ProteLyse lysates dentistry

Information References

Authors:

1. Altai State Medical University (kafedra terapevticheskoy stomatologii, zaveduyuschaya kafedroy, professor)
from 01.01.2002 to 01.01.2019
Barnaul, Barkaul, Russian Federation

2. Altai State Medical University (Department of Dental Dentistry, assistant professor)
from 01.01.2001 to 01.01.2019
Barnaul, Barkaul, Russian Federation

3. Altai State Medical University (Department of Dental Dentistry, assistant professor)
from 01.01.2015 to 01.01.2019
Barnaul, Barkaul, Russian Federation

Type:

Article

Pages:

from 58 to 63

Status:

Published

Subject area:

VAK Russia 14.01.2014
UDC 61
CSCSTI 76.29
Russian Classification of Professions by Education 31.07.01
Russian Library and Bibliographic Classification 566
BISAC MED016020 Dentistry / Dental Hygiene

Language:

Russian

Keywords:

periodontal inflammatory diseases, prevention, toothpaste, grapefruit extract, LysoTech and ProteLyse lysates, dentistry

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EVALUATION OF THE CLINICAL EFFECTIVENESS OF TOOTHPASTE CONTAINING GRAPEFRUIT EXTRACT AND LYSOTECH AND PROTELYSE LYSATES IN THE COMPLEX TREATMENT OF INFLAMMATORY PERIODONTAL DISEASES

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