employee
Ekaterinburg, Ekaterinburg, Russian Federation
employee
Ekaterinburg, Ekaterinburg, Russian Federation
Ekaterinburg, Ekaterinburg, Russian Federation
Ekaterinburg, Ekaterinburg, Russian Federation
employee
Ekaterinburg, Ekaterinburg, Russian Federation
employee
Ekaterinburg, Ekaterinburg, Russian Federation
employee
Ekaterinburg, Ekaterinburg, Russian Federation
employee
Ekaterinburg, Ekaterinburg, Russian Federation
Ekaterinburg, Ekaterinburg, Russian Federation
It is possible to increase the effectiveness of preventive dental measures by a differentiated approach to the use of toothpastes [3]. The most intensive incorporation of calcium and fluorides into the composition of the hard tissues of teeth occurs during their formation and mineralization [4, 5]. At the end of the growth and mineralization of the teeth, the enamel and dentin of the teeth become less permeable to fluoride, but the need for them does not disappear. Also, a number of authors note that the need for ions with different caries activity may differ. The purpose of our study was to study the effectiveness of the use of toothpastes in 6–7, 12, 15-year-old schoolchildren with various caries activity. We examined 532 children, attending organized children's groups in Yekaterinburg. By a randomization procedure based on the method of random numbers, children were divided into groups according to the type of paste used: calcium-containing, fluorine-containing, combined use of calcium and fluorine-containing pastes, paste based on organosilicon glycerohydrogel. The toothpastes effectiveness was assessed by the change in enamel resistance by functional methods: electrometry and Enamel Resistance Test. The annual increase in caries was taken into account. It was found that calcium-containing toothpastes are most effective in the first month of use, then the effect of their use weakens. Fluoride toothpastes lead to a persistent but slow increase in enamel resistance. The combined use of calcium and fluoride toothpastes gives a quick and lasting effect. A paste based on organosilicon glycerohydrogel gives a persistent decrease in enamel electrometry, with the best results in the group of schoolchildren with high caries activity.
schoolchildren, prevention, toothpaste, electrometry, enamel resistance
1. Ekimov E.V., Smetanin A.A. Povyshenie effektivnosti profilakticheskih meropriyatiy kariesa zubov v detskom vozraste s ispol'zovaniem remineraliziruyuschih sredstv. Stomatologiya detskogo vozrasta i profilaktika. 2018;3(66):18-22. [E.V. Ekimov, A.A. Smetanin. Increase of preventive care effectiveness of childhood dental caries with the use of remineralizing agents. Pediatric dentistry and prevention. 2018;3(66):18-22. (In Russ.)].
2. Kisel'nikova L.P., Li V., Shevchenko M.A. Ocenka effektivnosti primeneniya mestnoy remineralizuyuschey terapii na sozrevanie emali vremennyh zubov. Klinicheskaya stomatologiya. 2019;2(90):4-8. [L.P. Kisel'nikova, V. Li, M.A. Shevchenko. Evaluation of the effectiveness of the use of local remineralizing therapy for the maturation of the enamel of deciduous teeth. Clinical dentistry. 2019;2(90):4-8. (In Russ.)]. https://elibrary.ru/item.asp?id=37749511
3. Kuz'mina E.M., Yanushevich O.O., Kuz'mina I.N. Stomatologicheskaya zabolevaemost' naseleniya Rossii. Epidemiologicheskoe stomatologicheskoe obsledovanie naseleniya Rossii. Moskva : MGMSU. 2019:302. [E.M. Kuzmina, O.O. Yanushevich, I.N. Kuzmina. Dental morbidity in the population of Russia. Epidemiological dental examination of the population of Russia. Moscow : MGMSU. 2019:302. (In Russ.)].
4. Leont'ev V.K., Kisel'nikova L.P. Detskaya terapevticheskaya stomatologiya. Nacional'noe rukovodstvo. Moskva : GEOTAR-Media. 2017:952. [V.K. Leont'ev, L.P. Kisel'nikova. Children's therapeutic dentistry. National leadership. Moscow : GEOTAR-Media. 2017:952. (In Russ.)].
5. Mandra Yu.V., Bazarnyy V.V., Chupahin O.N., Honina T.G., Semencova E.A., Svetlakova E.N., Kotikova A.Yu., Legkih A.V., Polushina L.G., Teslenko A.Yu. Kliniko-morfologicheskaya ocenka effektivnosti primeneniya innovacionnoy lechebno-profilakticheskoy zubnoy pasty v kompleksnom lechenii pacientov molodogo vozrasta s osnovnymi stomatologicheskimi zabolevaniyami. Problemy stomatologii. 2017;13(3):29-35. [Yu.V. Mandra, V.V. Bazarnyy, O.N. Chupahin, T.G. Honina, E.A. Semencova, E.N. Svetlakova, A.Yu. Kotikova, A.V. Legkih, L.G. Polushina, A.Yu. Teslenko. Clinico-morphological estimation of efficiency of application of innovative treatment-and-prophylactic toothpaste in the complex treatment of young patients with basic dental diseases. Actual problems in dentistry. 2017;13(3):29-35. (In Russ.)]. https://elibrary.ru/item.asp?id=30109817
6. Moiseeva N.S., Haritonov D.Yu., Stepanov I.V. Povyshenie effektivnosti profilaktiki kariesa pri ispol'zovanii zubnoy pasty na polimernoy osnove, modificirovannoy elektromagnitnym polem. Vestnik novyh medicinskih tehnologiy. 2020;27(2):5-8. [N.S. Moiseeva, D.Yu. Kharitonov, I.V. Stepanov. Increasing the effectiveness of caries prevention when using a polymer-based toothpaste modified by an electromagnetic field. Bulletin of new medical technologies. 2020;27(2):5-8. (In Russ.)].
7. Naronova N.A. Molvinskih V.S. Belokonova N.A., Ol'shvang O.Yu. Effektivnost' remineralizuyuschey terapii u detey. Problemy stomatologii. 2019;15(3):47-54. [N.A. Naronova, V.S. Molvinskikh, N.A. Belokonova, O.Yu. Olschwang. The effectiveness of remineralizing therapy in children. Actual problems in dentistry. 2019;15(3):47-54. (In Russ.)]. https://elibrary.ru/item.asp?id=41212344
8. Smetanin A.A., Ekimov E.V., Skripkina G.I. Ionoobmennye processy v emali zubov i sredstva dlya ee remineralizacii (obzor literatury). Stomatologiya detskogo vozrasta i profilaktika. 2020;1(73):77-80. [A.A. Smetanin, E.V. Ekimov, G.I. Skripkina. Ion exchange processes in tooth enamel and means for its remineralization (literature review). Pediatric dentistry and prevention. 2020;1(73):77-80. (In Russ.)]. https://elibrary.ru/item.asp?id=42619545
9. Spicyna T.P., Nasretdinova N.Yu., Kotikova A.Yu., Mandra Yu.V. Effektivnost' primeneniya lechebno-profilakticheskih zubnyh past u shkol'nikov 15 let pri razlichnoy aktivnosti kariesa. Materialy VI Mezhdunarodnoy (76 Vserossiyskoy) nauchno-prakticheskoy konferencii «Aktual'nye voprosy sovremennoy medicinskoy nauki i zdravoohraneniya». 2021;(2):844-849. [T.P. Spitsyna, N.Yu. Nasretdinova, A.Yu. Kotikova, Yu.V. Mandra. The effectiveness of the use of therapeutic and prophylactic toothpastes in schoolchildren 15 years old with various caries activity. Materials of the VI International (76th All-Russian) scientific-practical conference "Topical issues of modern medical science and health care". 2021;(2):844-849. (In Russ.)].
10. Terehova T.N., Shakovec N.V., Mel'nikova E.I., Klenovskaya M.I., Naumovich D.N., Chernyavskaya N.D. Differencirovannyy podhod k profilaktike kariesa zubov u detey s razlichnoy veroyatnost'yu ego razvitiya. Stomatologiya detskogo vozrasta i profilaktika. 2020;3(75):211-215. [T.N. Terekhova, N.V. Shakovets, E.I. Mel'nikova, M.I. Klenovskaya, D.N. Naumovich, N.D. Chernyavskaya. Differentiated approach to the prevention of dental caries in children with different likelihood of its development. Pediatric dentistry and prevention. 2020;3(75):211-215.(In Russ.)]. https://elibrary.ru/item.asp?id=44036012
11. Amaechi B.T. et al. Comparative efficacy of a hydroxyapatite and a fluoride toothpaste for prevention and remineralization of dental caries in children // BDJ Open. – 2019;5:18.
12. Amaechi B.T., AbdulAzees P.A., Okoye L.O., Meyer F., Enax J. Comparison of hydroxyapatite and fluoride oral care gels for remineralization of initial caries: a pH-cycling study // BDJ Open. – 2020;6:9.
13. Aulestia F.J. et al. Fluoride exposure alters Ca2+ signaling and mitochondrial function in enamel cells // Sci. Signal. – 2020;13.
14. Basner R., Santamaria R.M., Schmoeckel J., Schüler E., Spliet C.H. Epidemiologische Begleituntersuchungen zur Gruppenprophylaxe 2016 // Deutsche Arbeitsgemeinschaft für Jugendzahnpflege. – 2017.
15. Buckeridge A., King N., Anthonappa R. Relationships between parental education, choice of child dentifrice, and their children's caries experience // Int J Paediatr Dent. – 2021;31(1):115-121. doi: 10.1111/ipd.12716. Epub 2020 Sep 10. PMID: 32815573.
16. Chrisopoulos S., Harford J.E. Oral health and dental care in Australia: key facts and figures 2015 // Australian Institute of Health and Welfare and the University of Adelaide. – 2016.
17. Enax J., Fabritius H.-O., Fabritius-Vilpoux K., Amaechi B.T., Meyer F. Modes of action and clinical efficacy of particulate hydroxyapatite in preventive oral health care—state of the art // Open Dent. J. – 2019;13:274-287.
18. Nasretdinova N., Mandra Yu.V., Bazarnyy V., Polushina L., Mandra E., Boldyrev Yu., Vlasova M., Dimitrova Yu. Age dynamics of dental and laboratory health indicators in Yekaterimburg children (5-6, 12, 15 years) // Actual problems in dentistry. – 2019;15(3):116-120. DOI:10.18481/2077-7566-2019-15-3-116-120
19. Oral Health Survey. Basic methods. 5th ed. Geneva. World Health Organization. – 2013:135.
20. Paszynska E., Pawinska M., Gawriolek M. et al. Impact of a toothpaste with microcrystalline hydroxyapatite on the occurrence of early childhood caries: a 1-year randomized clinical trial // Sci Rep. – 2021;11:2650. https://doi.org/10.1038/s41598-021-81112-y
21. Schlagenhauf U. et al. Impact of a non-fluoridated microcrystalline hydroxyapatite dentifrice on enamel caries progression in highly caries-susceptible orthodontic patients: a randomized, controlled 6-month trial // J. Invest. Clin. Dent. – 2019;10:e12399.
22. Strittholt C.A., McMillan D.A., He T., Baker R.A., Barker M.L. A randomized clinical study to assess ingestion of dentifrice by children // Regul. Toxicol. Pharmacol. – 2016;75:66–71.
23. Tinanoff N. et al. Early childhood caries epidemiology, aetiology, risk assessment, societal burden, management, education, and policy: global perspective // Int. J. Paediat. Dent. – 2019;29:238-248.
24. Walsh T., Worthington H.V., Glenny A.M., Marinho V.C., Jeroncic A. Fluoride toothpastes of different concentrations for preventing dental caries // Cochrane Database Syst. Rev. – 2019;3:Cd007868.
25. Wierichs R.J. et al. Effects of dentifrices differing in fluoride compounds on artificial enamel caries lesions in vitro // Odontology. – 2017;105:36-45.
26. Ya V., Turygin A.P., Sadovsky V.V., Mandra Yu.V., Sementsova E.A., Kotikova A.Yu., Legkikh A.V., Nikitina E.Yu., Bogdanova E.A., Sabirzyanov N.A. et al. Silicon-hydroxyapatite‒glycerohydrogel as a promising biomaterial for dental applications // Colloids and Surfaces B: Biointerfaces. – 2020;189:110851. DOI:10.1016/j.colsurfb.2020.110851
