EFFECT OF SILVER NANOPARTICLES ON BIOFILMS OF MICROORGANISMS (REVIEW)
Abstract and keywords
Abstract (English):
Nanotechnology enter in all spheres of human activity, particularly in medicine. Using nanoprogress allows the use of various nanostructures in the traditional methods therapy of various pathologies. The growing resistance to antibiotic drugs among human pathogens strains of microorganisms requires the development of alternatives. Silver nanoparticles are current contenders for the role of an alternative to modern antibiotics. They are able to transfer therapeutic agents, act on the membrane of microbial cells, disrupting their livelihoods and leading to death, as they are less toxic than silver ions. The use of nanoparticles is an effective tool in combating formed biofilms on medical supplies, and prevent to their education. Nanoparticles have proved positively against many antibiotic-resistant strains of microorganisms, including planktonic phase P. aureginosa. Synergistic effect observed while using of nanoparticles and various antibiotics. Antibacterial properties studied in experimental models of peritonitis and meningoencephalitis. In case of peritonitis high efficiency.

Keywords:
silver nanoparticles resistance, biofilm, strains, bacteria, nanotechnology.
References

1. De Vindt V., Verkauteren T., Vestrate V. Sposob polucheniya kompozitsii, soderzhashchey kolloidnoe nanoserebro ili nanozoloto. Patent № 2460797. Yanssen Farmatsevtika N. V. 2010.

2. Khrenov P.A., Chestnova T.V. Obzor metodov bor´by s mikrobnymi bioplenkami pri vospalitel´nykh zabolevaniyakh. Vestnik novykh meditsinskikh tekhnologiy. Elektronnoe izdanie. 2013. №1. Publikatsiya 2-13. URL: http://www.medtsu.tula.ru/VNMT/Bulletin/E2013-1/4102.pdf (data obrashcheniya: 01.02.2013).

3. Savin E.I., Subbotina T.I., Khadartsev A.A., Khrenov P.A., Chestnova T.V., Buzulukov Yu.P., Antsiferova A. N. Eksperimental´noe issledovanie antibakterial´noy aktivnosti nanochastits serebra na modeli peritonita i meningoentsefalita in vivo. Vestnik novykh meditsinskikh tekhnologiy. Elektronnoe izdanie. 2014. № 1. Publikatsiya 2-21. URL: http://www.medtsu.tula.ru/VNMT/Bulletin/E2014-1/4793.pdf (data obrashcheniya: 30.04.2014).

4. Khrenov P.A., Chestnova T.V. Effekt dimetilsul´foksida v otnoshenii bioplenkoobrazovaniya shtammami Staphylococcus aureus. Mezhdunarodnyy zhurnal prikladnykh i fundamental´nykh issledovaniy. 2014. № 5-1. S. 140–141.

5. Khrenov P.A., Chestnova T.V., Adgezivnyy potentsial gramotritsatel´noy ranevoy flory pod vliyaniem preparata «Dimeksid». Mezhdunarodnyy zhurnal prikladnykh i fundamental´nykh issledovaniy. 2014. № 1. S. 92.

6. Khrenov P.A., Chestnova T.V. Eksperimental´noe izuchenie vliyaniya preparata «Dimeksid» na virulentnye svoystva Staphylococcus aureus izolirovannykh iz ran. Vestnik novykh meditsinskikh tekhnologiy. 2013. T. 20. № 2. S. 405–408.

7. Trezubov V.N., Semenov S.S., Afinogenov G.E., Afinogenova A.G., Sapronova O.N. Sozdanie antibakterial´nogo materiala, soderzhashchego nanoserebro, dlya bazisov s´´emnykh zubnykh protezov. Institut stomatologii. 2010. T. 2. № 47. S. 22–23.

8. Mosin O. V. Bakteritsidnye svoystva nanochastits kolloidnogo serebra. Nanotekhnologii. Ekologiya. Proizvodstvo. 2013. № 6 (25). S. 54–59.

9. Khrenov P.A., Chestnova T.V. Vliyanie dimetilsul´foksida na adgezivnuyu aktivnost´ Staphylococcus aureus izolirovannogo iz ran. Mezhdunarodnyy zhurnal eksperimental´nogo obrazovaniya. 2013. № 6. S. 47.

10. Chestnova T.V., Khrenov P.A. Pokazateli gemogrammy u detey s ostroy kishechnoy infektsiey, vydelyayushchikh griby roda Candida. Mezhdunarodnyy zhurnal prikladnykh i fundamental´nykh issledovaniy. 2013. № 8. S. 162–163.

11. Chestnova T. V., Seregina N. V. Sravnitel´nyy analiz mikrobnogo peyzazha vozbuditeley, vydelennykh iz krovi likhoradyashchikh bol´nykh. Vestnik novykh meditsinskikh tekhnologiy. 2012. № 2. S. 63–65.

12. Chestnova T. V., Seregina N. V. Osobennosti sushchestvovaniya bakteriy v sostave bioplenok na primere uropatogennykh kishechnykh palochek. Vestnik novykh meditsinskikh tekhnologiy. 2010. T. 17. № 4. S. 28–30.

13. Chestnova T.V. Prospektivnoe populyatsionnoe izuchenie zabolevaemosti gnoynymi meningitami u detey v vozraste ot 5 do 8 let v gorodakh Rossii. Epidemiologiya i infektsionnye bolezni. 2009. № 4. S. 33–43.

14. Chestnova T. V., Seregina N. V., Khromushin V. A. Obzor biofizicheskikh osobennostey mikrobnoy adgezii. Vestnik novykh meditsinskikh tekhnologiy. 2008. T. 15. № 4. S. 175–178.

15. Chestnova T. V., Seregina N. V. Izuchenie vliyaniya atsetonovogo ekstrakta organicheskoy massy shungitovoy porody na adgezivnye svoystva enetrobakteriy. Vestnik novykh meditsinskikh tekhnologiy. 2008. № 4. T. 15. S. 168–170.

16. Chestnova T. V., Seregina N.V. Ingibirovanie proteoliticheskikh i sakharoliticheskikh fermentov Pseudomonas aureginosa pod deystviem ekstrakta shungita. Vestnik novykh meditsinskikh tekhnologiy. 2008. № 4. T. 15. 167–168.

17. Chestnova T.V., Seregina N.V. Adaptivnye mekhanizmy i ustoychivost´ sal´monell k deystviyu uksusno-kislotnogo ekstrakta organicheskogo ekstrakta organicheskoy massy shungitovoy porody. Vestnik novykh meditsinskikh tekhnologiy. 2007. № 4. S. 207.

18. Chestnova T. V., Seregina N. V. Vliyanie etanol´nogo ekstrakta organicheskoy massy shungitovoy porody na kul´turu β- gemoliticheskogo streptokokka. Vestnik novykh meditsinskikh tekhnologiy. 2007. № 4. S. 64.

19. Terminology and definitions for nano-objects. Nanoparticle, nanofibre and nanoplate. ISO/TS 27687:2008.

20. Christopher P. Randall, Linda B. Oyama, Julieanne M. Bostock, Ian Chopra and Alex J. O’Neill. The silver cation (Ag+): antistaphylococcal activity, mode of action and resistance studies. Jour. Antimicrob. Che-mother. 2013; 68: P. 131–138.

21. Chen X., Schluesener H. J. Nanosilver: a nanoproduct in medical application. Toxicol. Lett. 2008. V. 176. № 2. P. 359–362.

Login or Create
* Forgot password?