graduate student
Dental clinic "Elite" (Department of Therapeutic Dentistry with the course of ICPE dentist-therapist)
employee
Ufa, Kazan, Russian Federation
employee
Ufa, Ufa, Russian Federation
employee
Ufa, Ufa, Russian Federation
Bashkir State University (Scientific Laboratory for the Study of Social and Economic Problems, Head of the Scientific Laboratory)
Ufa, Ufa, Russian Federation
employee
Ufa, Kazan, Russian Federation
graduate student
Ufa, Ufa, Russian Federation
The purpose of the study is to evaluation of peculiarities of complaints, symptoms and clinical manifestations of typical asymptomatic (L43.80) and erosive-ulcerative (L43.82) forms of lichen planus (LP), its manifestations on the oral mucosa, depending on the age and sex of patients. Material and methods. In the present study, 111 patients with OLP were divided into a main clinical group with erosive-ulcerative form of OLP (L43.82, n = 86) and a comparison group with typical asymptomatic form of OLP (L43.80, n = 25) based on the complex of dental examination and simple randomization method. Mann–Whitney and chi-square tests, including Yates' correction, were used to assess the statistical significance of differences between the groups. Results. Patients with the typical asymptomatic form of OLP (L43.80) often had grayish-white, flat papules up to 2 mm in diameter on the unchanged mucosa of the cheeks and dorsal surface of the tongue in the absence of complaints. In the erosive and ulcerative form (L43.82) of OLP, the complaints of pain, intensifying at intake of hard, spicy and hot food, feeling of tightness, roughness, burning, slight dryness prevailed, papules, erosions of irregular or polygonal ulcers were simultaneously observed on swollen, hyperemic mucosa of cheeks, corners of mouth and lateral surface of tongue. The studied pathology prevailed in 81.98% of cases in persons of young working age. Depending on the form of OLP, the intensity of caries according to the CPU index corresponds to a high or very high degree of caries process, the state of oral hygiene according to the OHI-S index of poor or poor hygiene, the inflammatory process in periodontal tissues according to the PMA index of mild or medium degree of inflammation (p < 0.001). Conclusion: thus, the identified features of complaints, symptoms and manifestations of oral mucosal lichen planus should be taken into account by general practitioners when conducting outpatient appointments.
red squamous lichen, oral mucosa, pain, burning, dryness, dental status
1. Anisimova I.V., Simonyan L.A. Chastota sochetaniya krasnogo ploskogo lishaya s somaticheskoy patologiey i mestnymi neblagopriyatnymi faktorami polosti rta. Problemy stomatologii. 2019;1(15):16-22. [I. Anisimova, L. Simonyan. The frequency of combination of oral lichen planus with somatic pathology and local unfavorable factors of the oral cavity. Actual problems in dentistry. 2019;1(15):16-22. (In Russ.)]. https://elibrary.ru/item.asp?id=37602574
2. Belyaeva Yu.G., Lukina G.I., Abramova M.Ya. Chastnye voprosy diagnostiki i lecheniya erozivno-yazvennoy formy ploskogo lishaya. Rossiyskaya stomatologiya. 2022;15:2:36-37. [Y.G. Belyaeva, G.I. Lukina, M.Ya. Abramova. Specific issues of diagnosis and treatment of erosive and ulcerative forms of squamous lichen planus. Russian dentistry. 2022;15:2:36-37. (In Russ.)]. https://elibrary.ru/item.asp?id=48680552
3. Ibragimova M.H., Murodova Z.U., SamadovaSh. I. Krasnyy ploskiy lishay polosti rta. Klinika i lechenie. Stomatologiya. 2020;4:45-48. [M.Kh. Ibragimova, Z.U. Murodova, Sh.I. Samadova. Lichen planus of the oral cavity. Clinic and treatment. Stomatologiya. 2020;4:45-48. (In Russ.)]. https://doi.org/10.34920/2091-5845-2020-94
4. Slesarenko N.A., Utc S.R., Bakulev A.L., Eremina M.G., Sherstneva V.N. Klinicheskiy polimorfizm krasnogo ploskogo lishaya. Saratovskiy nauchno-medicinskiy zhurnal. 2017;3(13):652-661. [N.A. Slesarenko, S.R. Utz, A.L. Bakulev, M.G. Eremina, V.N. Sherstneva. Clinical polymorphism of lichen ruber planus. Saratov Journal Of Medical Scientific Research. 2017;3(13):652-661. (In Russ.)]. https://elibrary.ru/item.asp?id=32484262
5. Olisova O.Yu. i dr. Krasnyy ploskiy lishay. Rossiyskiy zhurnal kozhnyh i venericheskih bolezney. 2020;23;5:356-360. [O.Yu. Olisova et al. Lichen planus. Russian Journal of Skin and Venereal Diseases. 2020;23;5:356-360. (In Russ.)]. https://doi.org/10.17816/dv59113
6. Dorozhenok I.Yu., Snarskaya E.S., Shenberg V.G. Krasnyy ploskiy lishay i associirovannye psihosomaticheskie rasstroystva. Vestnik dermatologii i venerologii. 2016;4:27-32. [I.Yu. Dorozhenok, E.S. Snarskaya, V.G. Shenberg. Lichen planus and associated psychosomatic disorders. Bulletin of dermatology and venereology. 2016;4:27-32. (In Russ.)]. https://elibrary.ru/item.asp?id=26552382
7. Potekaev N.N., Zhukova O.V., Tereschenko A.V. i dr. Krasnyy ploskiy lishay slizistoy obolochki polosti rta: klinika, diagnostika, lechenie, profilaktika. Metodicheskie rekomendacii. Moskva : Departament zdravoohraneniya goroda Moskvy. 2021:27. [N.N. Potekaev, O.V. Zhukova, A.V. Tereschenko et al. Red squamous lichen of the oral mucosa: clinic, diagnosis, treatment, prevention. Guidelines. Moscow : Department of Health of Moscow. 2021:27. (In Russ.)]. https://elibrary.ru/item.asp?id=44900675
8. Krivencev A.E., Popkov V.S. Krasnyy ploskiy lishay slizistoy polosti rta v praktike vracha - stomatologa-hirurga. Vestnik Volgogradskogo gosudarstvennogo medicinskogo universiteta. 2021;1;77:40-43. [A.E. Kriventsev, V.S. Popkov. Red flat lichen of the oral mucosa in the practice of a dentist-surgeon. Journal of Volgograd state medical university. 2021;1;77:40-43.(In Russ.)]. https://doi.org/10.19163/1994-9480-2021-1(77)-40-43
9. Dorozhenok I.Yu., Snarskaya E.S., Mihaylova M.V. Krasnyy ploskiy lishay, COVID-19 i depressiya: psihosomaticheskie korrelyacii. Zhurnal nevrologii i psihiatrii im. C.C. Korsakova. 2022;122;1:122-125. [I.Yu. Dorozhenok, E.S. Snarskaya, M.V. Mikhailova. Lichen planus, COVID-19 and depression: psychosomatic correlations. S.S. Korsakov Journal of Neurology and Psychiatry. 2022;122;1:122-125. (In Russ.)]. https://doi.org/10.17116/jnevro2022122011122
10. Kubanova A.A., Kubanov A.A., Olisova O.Yu., Chikin V.V., Mineeva A.A. Krasnyy ploskiy lishay. Federal'nye klinicheskie rekomendacii. Dermatovenerologiya. Bolezni kozhi. Infekcii, peredavaemye polovym putem. Moskva. 2016:212-225. [A.A. Kubanova, A.A. Kubanov, O.Yu. Olisova, V.V. Chikin, A.A. Mineeva. Red lichen planus. Federal clinical recommendations. Dermatovenerology. Diseases of the skin. Sexually transmitted infections. Moscow. 2016:212-225. (In Russ.)]. https://elibrary.ru/item.asp?id=43829144
11. Makedonova Yu.A. Optimizaciya patogeneticheskoy terapii bol'nyh krasnym ploskim lishaem slizistoy obolochki polosti rta : 14.01.14 : dissertaciya na soiskanie uchenoy stepeni kandidata medicinskih nauk. FGBOU VO «Volgogradskiy gosudarstvennyy medicinskiy universitet» Ministerstva zdravoohraneniya Rossiyskoy Federacii. 2018:338. [Yu.A. Makedonova. Optimization of pathogenetic therapy of patients with red squamous lesions of the oral mucosa : 14.01.14 : dis. ... thesis for the degree of candidate of medical sciences. FGBOU VO "Volgograd State Medical University" of the Ministry of Health of the Russian Federation. 2018:338. (In Russ.)]. https://elibrary.ru/item.asp?id=41222820
12. Molochkov V.A., Amhadova M.A., Molochkova Yu.V. Krasnyy ploskiy lishay polosti rta kak mezhdisciplinarnaya problema. Medicinskiy alfavit. 2017;4(38):52-57. [V.A. Molochkov, M.A. Amkhadova, Yu.V. Molochkova. Oral lichen planus as interdisciplinary problem. Medical alphabet. 2017;4(38):52-57. (In Russ)]. https://elibrary.ru/item.asp?id=32368114
13. Gur'evskaya O.A., Livzan M.A., Usmanova I.N. i dr. Nekotorye osobennosti klinicheskoy manifestacii tipichnyh i oslozhnennyh form krasnogo ploskogo lishaya na slizistoy obolochke rta po dannym nablyudeniya. Problemy stomatologii. 2021;17(1):63-69. [O.A. Guryevskaya, M.A. Livzan, I.N. Usmanova et. al. Some features of clinical manifestation of typical and complicated forms of lichen planus on the oral mucosa according to observation data. Actual problems in dentistry. 2021;17(1):63-69. (In Russ.)]. https://doi.org/10.18481/2077-7566-20-17-1-63-69
14. Adamovich E.I., Makedonova Yu.A., Marymova E.B., Pavlova-Adamovich A.G. Obosnovanie novyh metodov diagnostiki i lecheniya erozivno-yazvennoy formy krasnogo ploskogo lishaya slizistoy polosti rta. Sovremennye problemy nauki i obrazovaniya. 2016;1:27. [E.I. Adamovich, Yu.A. Makedonova, E.B. Marymova, A.G. Pavlova-Adamovich. Ustification of new methods of diagnosis and treatment of erosive-ulcerous form planus of the oral mucosa. Contemporary issues of science and education. 2016;1:27. (In Russ)]. https://elibrary.ru/item.asp?id=25509274
15. Ravodin R.A. i dr. Osobennosti sovremennogo klinicheskogo techeniya krasnogo ploskogo lishaya. Problemy medicinskoy mikologii. 2020;22;3:119-120. [R.A. Ravodin et al. Features of the modern clinical course of lichen planus. Problems of Medical Mycology. 2020;22(3):119-120. (In Russ.)]. https://elibrary.ru/item.asp?id=44271853
16. Gur'evskaya O.A., Usmanova I.N., Senina V.O., Yunusova R.D. Ocenka simptomov boli, suhosti, zhzheniya pri razlichnyh formah ploskogo lishaya slizistoy obolochki rta. Rossiyskaya stomatologiya. 2022;15;2:41-43. [O.A. Guryevskaya, I.N. Usmanova, V.O. Senina, R.D. Yunusova. Evaluation of symptoms of pain, dryness, burning in various forms of squamous lichen planus of the oral mucosa. Russian dentistry. 2022;15;2:41-43. (In Russ.)]. https://elibrary.ru/item.asp?id=48680555
17. Gileva O.S., Koshkin S.V., Libik T.V. i dr. Parodontologicheskie aspekty zabolevaniy slizistoy obolochki polosti rta: krasnyy ploskiy lishay. Parodontologiya. 2017;22;3(84):9-14. [O.S. Gileva, S.V. Koshkin, T.V. Libik et al. Periodontological aspects of oral mucosal diseases: lichen planus mucosa. Periodontology. 2017;22;3(84):9-14. (In Russ.)]. https://elibrary.ru/item.asp?id=30060549
18. Rabinovich, O.F., Rabinovich I.M., Babichenko I.I. Krasnyy ploskiy lishay slizistoy obolochki rta. Moskva : Rossiyskaya akademiya nauk. 2018:80. [O.F. Rabinovich, I.M. Rabinovich, I.I. Babichenko. Red squamous lichen of oral mucosa. Moscow : Russian Academy of Sciences. 2018:80. (In Russ.)]. https://elibrary.ru/item.asp?id=37598471
19. Fazylova Yu.V., Fatihova R.R., Blashkova S.L. Sovremennye principy lecheniya proyavleniy krasnogo ploskogo lishaya na slizi-stoy obolochke rta. Molodoy uchenyy. 2018;24(210):289-293. [Yu.V. Fazilova, R.R. Fatikhova, S.L. Blashkova. Modern principles of the treatment of manifestations of squamous lichen planus on the oral mucosa. Young Scientist. 2018;24(210):289-293. (In Russ.)]. https://elibrary.ru/item.asp?id=35127699
20. Surdina E.D., Silin A.V., Rodionov G.G. Kriterii ocenki tyazhesti techeniya krasnogo ploskogo lishaya slizistoy obolochki rta. Medicinskiy al'yans. 2021;9;1:73-81. [E.D. Surdina, A.V. Silin, G.G. Rodionov. Criteria for assessing the severi-ty of lichen planus of the oral mucosa. Medical Alliance. 2021;9;1:73-81. (In Russ.)]. https://elibrary.ru/item.asp?id=45596276
21. Titarenko M.A., Stolyarova V.A., Sysolyatin P.G., Baydik O.D. Rol' gastrointestinal'noy patologii v razvitii i tyazhesti techeniya krasnogo ploskogo lishaya slizistoy obolochki polosti rta. Byulleten' sibirskoy mediciny. 2018;17(3):151-156. [M.A. Titarenko, V.A. Stolyarova, P.G. Sysolyatin, O.D. Baydik. The role of gastrointestinal pathology in the development and severity of oral lichen planus. Bulletin of siberian medicine. 2018;17(3):151-156. (In Russ.)]. https://doi.org/10.20538/1682-0363-2018-3-151–156
22. Ion D.I., Settefield J.F. Oral lichen planus // Prim. Dent. J. – 2016;5;1:40-44. https://doi.org/10.1177/205016841600500104
23. Raja S.N. et al. The revised International Association for the Study of Pain definition of pain: concepts, challenges, and compromises // Pain. – 2020;161;9:1976-1982. https://doi.org/10.1097/j.pain.0000000000001939
24. Tovaru S., Parlatescu I.M., Nicolae C.L., Tovaru M. Oral llchen planus and malignancy // Abstracts of EAOM-meeting. – 2018. https://doi.org/10.1155/2018/1959506