Stoma ( dental surgeon)
Novokuznetsk, Kemerovo, Russian Federation
Regional Society of Maxillofacial Surgeons ( teacher)
Novokuznetsk, Kemerovo, Russian Federation
The subject of the study is the main properties of ceramic dental implants. Objectives. A systematic analysis of modern domestic and foreign literary sources to determine the main advantages of ceramic dental implants. Methodology. The study was based on the search and study of original articles on the dental implantology in the databases: Russian State Library, eLibrary, PubMed, The Cochrane Library, Google Scholar. The main selection of materials was carried out by keywords. Results. Currently, dental ceramic implants are attracting more and more attention from both dentists and patients. Every year, the clinical use of ceramic implants is becoming wider. Only in Europe every year there are 3 major congresses on ceramic implantology. In many countries, the number of associations dealing with this particular topic has increased, ceramic implants have unlimited potential for clinical use. Numerous studies show that the clinical use of zirconium oxide implants is practically not accompanied by manifestations of peri-implantitis, and gum epithelial tissues are able to firmly and reliably attach to their surface. Zirconium forms a dense ZrO2 dioxide film on the surface with good protective properties. Zirconia is bioinert to other materials found in the oral cavity and is particularly suitable for patients who are allergic or intolerant to metals. The latest materials and techniques, which include zirconium dioxide, have important advantages, and its use as dental implants significantly increases the clinical effectiveness of treatment. Therefore, when planning dental implantation, preference should be given to zirconia implants, which will avoid the development of a negative effect of treatment on both organs and tissues of the oral cavity, and the body as a whole. Conclusions. The review of literature sources on the effectiveness of ceramic dental implants showed evidence-based possibilities for the clinical use of this type of implants in modern dentistry.
dental implantation, implants, zirconium dioxide, titanium, ceramic implants
1. Biben A.V., Ozhogan Z.R. Tribologicheskoe ispytanie stomatologicheskih esteticheskih konstrukcionnyh materialov. Vestnik stomatologii. 2018;3:41-46. [A.V. Biben, Z.R. Ozhogan. Tribological testing of dental aesthetic structural materials. Bulletin of dentistry. 2018;3:41-46. (In Russ.)]. https://elibrary.ru/item.asp?id=36769822
2. Butenko O.G., Topol'nickiy O.Z., Romodanovskiy P.O. Nekotorye aspekty sudebno-medicinskoy ocenki defektov medicinskoy pomoschi pri okazanii stomatologicheskogo lecheniya pri ispol'zovanii ortopedicheskih konstrukciy na dental'nyh implantatah s vozniknoveniem sindroma gal'vanizm. Stomatologiya dlya vseh. 2020;1(90):24-27. [O.G. Butenko, O.Z. Topolnitsky, P.O. Romodanovsky. Some aspects of forensic medical assessment of medical care defects in the provision of dental treatment when using orthopedic structures on dental implants with the occurrence of galvanism syndrome. Dentistry for everyone. 2020;1(90):24-27 (In Russ.)]. https://elibrary.ru/item.asp?id=42634723
3. Grechishnikov N.S. Metody diagnostiki gal'vanoza. Nauchnoe obozrenie. Medicinskie nauki. 2017;4:7-11. [N.S. Grechishnikov. Methods for diagnosing galvanosis. Scientific review. Medical Sciences. 2017;4:7-11. (In Russ.)]. https://elibrary.ru/item.asp?id=28781644
4. Dubova L.V., Manin O.I., Romanenko M.V., Giryaev S.G. Ocenka pokazateley raznosti elektrohimicheskih potencialov u pacientov s neperenosimost'yu k materialam zubnyh protezov s oporoy na dental'nye implantaty. Aktual'nye voprosy stomatologii. Sbornik nauchnyh trudov, posvyaschennyy osnovatelyu kafedry ortopedicheskoy stomatologii KGMU professoru Isaaku Mihaylovichu Oksmanu. Kazan'. 2021:579-582. [L.V. Dubova, O.I. Manin, M.V. Romanenko, S.G. Giryaev. Evaluation of the indicators of the difference in electrochemical potentials in patients with intolerance to the materials of dentures based on dental implants. Topical issues of dentistry. A collection of scientific papers dedicated to the founder of the Department of Orthopedic Dentistry of KSMU, Professor Isaac Mikhailovich Oksman. Kazan. 2021:579-582. (In Russ.)]. https://elibrary.ru/item.asp?id=45687300
5. Karpuk I.Yu. Immunopatogenez, immunoallergodiagnostika i profilaktika neperenosimosti stomatologicheskih materialov : avtoref. Dis. … d-ra med.nauk. Vitebsk, 2018:49. [I.Yu. Karpuk. Immunopathogenesis, immunoallergodiagnostics and prevention of intolerance to dental materials : abstract dis. … doctor of medical sciences. Vitebsk, 2018:49. (In Russ.)]. https://science-medicine.ru/ru/article/view?id=989
6. Kristal' E.A., Levickaya M.V. Diagnostika i lechenie gal'vanizma. Sovremennye nauchnye issledovaniya i innovacii. 2017;3:664-666. [E.A. Kristal, M.V. Levitskaya. Diagnosis and treatment of galvanism. Modern scientific research and innovation. 2017;3:664-666. (In Russ.)]. https://elibrary.ru/item.asp?id=29002391
7. Lebedev K.A., Yanushevich O.O., Mitronin A.V. i dr. K voprosu allergoneperenosimosti na stomatologicheskie materialy u pacientov s sindromom gal'vanizma. Sovremennaya stomatologiya – effektivnost' profilaktiki i lecheniya. Nanotehnologii v stomatologii. Tver'. 2014:167-172. [K.A. Lebedev, O.O. Yanushevich, A.V. Mitronin. On the issue of allergy to dental materials in patients with galvanism syndrome. Modern dentistry - the effectiveness of prevention and treatment. Nanotechnology in dentistry. Tver. 2014:167-172. (In Russ.)]. https://elibrary.ru/item.asp?id=49244490
8. Manin O.I., Zolotnickiy I.V., Romanenko M.V., Rudakova A.M. Analiz zhalob u pacientov s yavleniyami neperenosimosti zubnyh protezov s oporoy na dental'nye implantaty. Rossiyskaya stomatologiya. 2022;15(3):52-53. [O.I. Manin, I.V. Zolotnitsky, M.V. Romanenko, A.M. Rudakova. Analysis of complaints in patients with symptoms of intolerance to dental prostheses based on dental implants. Russian dentistry. 2022;15(3):52-53. (In Russ.)]. https://elibrary.ru/item.asp?id=49387856
9. Manina E.I., Barinov E.H., Manin A.I., Manin O.I. Neperenosimost' stomatologicheskih konstrukcionnyh materialov, ispol'zuyuschihsya pri izgotovlenii zubnyh protezov. Medicinskoe pravo: teoriya i praktika. 2017;3:1(5):298-304. [E.I. Manina, E.Kh. Barinov, A.I. Manin, O.I. Manin. Intolerance to dental structural materials used in the manufacture of dentures. Medical law: theory and practice. 2017;3:1(5):298-304. (In Russ.)]. https://elibrary.ru/item.asp?id=29712639
10. Mau O. Dioksid cirkoniya v sochetanii so spekaemym metallom. Novoe v stomatologii. 2018;7:32-36. [O. Mau. Zirconium dioxide in combination with sintered metal. New in dentistry. 2018;7:32-36. (In Russ.)]. https://elibrary.ru/item.asp?id=47248531
11. Ovcharenko E.N., Zhad'ko S.I., Kolbasin P.N. Nikol'skaya V.A. Vliyanie splavov metallov ortopedicheskih konstrukciy na processy svobodnoradikal'nogo okisleniya v rotovoy zhidkosti. Zhurnal Grodnenskogo gosudarstvennogo medicinskogo universiteta. 2014;3: 45-48. [E.N. Ovcharenko, S.I. Zhadko, P.N. Kolbasin, V.A. Nikolskaya. Influence of metal alloys of orthopedic constructions on the processes of free radical oxidation in the oral fluid. Journal of Grodno State Medical University. 2014;3:45-48. (In Russ.)]. https://elibrary.ru/item.asp?id=22133199
12. Oganyan A.I., Apresyan S.V., Akulovich A.V. Shtiftovye konstrukcii iz dioksida cirkoniya, primenyaemye v razlichnyh uchastkah zubnogo ryada. Rossiyskiy stomatologicheskiy zhurnal. 2017;3:135-137. [A.I. Oganyan, S.V. Apresyan, A.V. Akulovich. Zirconia pin constructions used in various parts of the dentition. Russian Dental Journal. 2017;3:135-137. (In Russ.)]. https://elibrary.ru/item.asp?id=29460145
13. Olesov E.E., Nikitin V.V., Glazkova E.V., Olesova V.N., Stepanov A.F. Personificirovannyy podhod k profilaktike vospalitel'nyh oslozhneniy dental'noy implantacii. Kurortnaya medicina. 2017;3:188-190. [E.E. Olesov, V.V. Nikitin, E.V. Glazkova, V.N. Olesova, A.F. Stepanov. Personalized approach to the prevention of inflammatory complications of dental implantation. Spa medicine. 2017;3:188-190. (In Russ.)]. https://elibrary.ru/item.asp?id=30280669
14. Redinov I.S., Kozhevnikov S.V., Shevkunova N.A. i dr. Diagnostika neperenosimosti ortopedicheskih konstrukcionnyh materialov na fone gal'vanoza u pacientov stomatologicheskogo priema. Trudy Izhevskoy gosudarstvennoy medicinskoy akademii. Izhevsk : FGBOU VPO "Izhevskaya gosudarstvennaya medicinskaya akademiya" MZ RF; 2020;122-124. [I.S. Redinov, S.V. Kozhevnikov, N.A. Shevkunova. Diagnosis of intolerance to orthopedic structural materials against the background of galvanosis in dental patients. Proceedings of the Izhevsk State Medical Academy. Sat. scientific articles. Izhevsk : FGBOU VPO "Izhevsk State Medical Academy" of the Ministry of Health of the Russian Federation. 2020;122-124. (In Russ.)]. https://elibrary.ru/item.asp?id=44509882
15. Romanenko M.V., Manin O.I., Giryaev S.G. Sravnitel'naya ocenka pokazateley raznosti elektrohimicheskih potencialov mezhdu implantatami raznyh firm-proizvoditeley i konstrukcionnymi materialami v usloviyah, imitiruyuschih agressivnuyu sredu rotovoy zhidkosti. Ros. Stomatologiya. 2021;14;2:61-62. [M.V. Romanenko, O.I. Manin, S.G. Giryaev. Comparative assessment of the indicators of the difference in electrochemical potentials between implants from different manufacturers and structural materials under conditions simulating the aggressive environment of the oral fluid. Ros. Dentistry. 2021;14;2:61-62. (In Russ.)]. https://elibrary.ru/item.asp?id=46224704
16. Romanenko M.V., Manin O.I., Rudakova A.M. Analiz individual'noy chuvstvitel'nosti k konstrukcionnym materialam u pacientov s zubnymi protezami s oporoy na dental'nye implantaty, pred'yavlyayuschih zhaloby na yavleniya neperenosimosti. Stomatologicheskaya vesna v Belgorode. 2022:205-207. [M.V. Romanenko, O.I. Manin, A.M. Rudakova. Analysis of individual sensitivity to structural materials in patients with dentures based on dental implants, who complain of intolerance phenomena. Dental spring in Belgorod. 2022:205-207. (In Russ.)]. https://elibrary.ru/item.asp?id=49339896
17. Skal'nyy A.A. Fizicheskaya aktivnost' i obmen mikroelementov. Mikroelementy v medicine. 2020;21(2):3-12. [A.A. Skalny. Physical activity and micronutrient metabolism. Microelements in medicine. 2020;21(2):3-12. (In Russ.)]. https://elibrary.ru/item.asp?id=43043157
18. Smirnov A.S., Maksimenko L.L., Bagaev S.I. Kompromiss mezhdu prochnost'yu i biosovmestimost'yu. Stomatolog. 2017;1:22-24. [A.S. Smirnov, L.L. Maksimenko, S.I. Bagaev. A compromise between strength and biocompatibility. Dentist. 2017;1:22-24. (In Russ.)]. https://elibrary.ru/item.asp?id=28362573
19. Tebenova G.M., Askarova Sh.N., Safarov T.S. Puti resheniya diagnostiki neperenosimosti k metallicheskim vklyucheniyam v polosti rta. Vestnik Kazahskogo Nacional'nogo medicinskogo universiteta. 2018;1:541-544. [G.M. Tebenova, Sh.N. Askarova, T.S. Safarov. Ways to solve the diagnosis of intolerance to metal inclusions in the oral cavity. Bulletin of the Kazakh National Medical University. 2018;1:541-544. (In Russ.)]. https://elibrary.ru/item.asp?id=34989947
20. Titov P.L., Moyseychik P.N. Immunnyy status pacientov s zhalobami na neblagopriyatnoe deystvie dental'nyh splavov. Novye metody profilaktiki, diagnostiki i lecheniya v stomatologii. Minsk. 2017:433-439. [P.L. Titov, P.N. Moiseichik. The immune status of patients with complaints about the adverse effects of dental alloys. Sat. New methods of prevention, diagnosis and treatment in dentistry. Minsk. 2017:433-439. (In Russ.)]. https://elibrary.ru/item.asp?id=32416307
21. Filippenkova L.O., Galatenko N.A., Rozhnova R.A. i dr. Sravnenie biosovmestimosti obrazcov materialov dlya izgotovleniya nes'emnyh ortopedicheskih stomatologicheskih konstrukciy s pomosch'yu implantacionnogo testa. Sovremennaya stomatologiya. 2016;4:92-94. [L.O. Filippenkova, N.A. Galatenko, R.A. Rozhnova. Comparison of the biocompatibility of material samples for the manufacture of fixed orthopedic dental structures using an implantation test. Modern dentistry. 2016;4:92-94. (In Russ.)]. https://elibrary.ru/item.asp?id=36367550
22. Cholokova G.S., Yuldashev I.M., Tynalieva D.M., Abykeeva R.S. Profilaktika stomatologicheskih zabolevaniy – prioritetnoe napravlenie stomatologii. Sovremennye tendencii razvitiya nauki i tehnologiy. 2017;2-4:94-104. [G.S. Cholokova, I.M. Yuldashev, D.M. Tynalieva, R.S. Abykeeva. Prevention of dental diseases is a priority in dentistry. The current state of development of science and technology. 2017;2-4:94-104. (In Russ.)]. https://elibrary.ru/item.asp?id=28784153
23. Shumakov F.G. Eksperimental'no-klinicheskoe sravnenie keramicheskih i titanovyh dental'nyh implantatov : avtoref. dis. … kand. med. nauk. Moskva, 2018:24. [F.G. Shumakov. Experimental and clinical comparison of ceramic and titanium dental implants : abstract dis. … cand. med. sciences. Moscow, 2018:24. (In Russ.)]. https://www.dissercat.com/content/eksperimentalno-klinicheskoe-sravnenie-keramicheskikh-i-titanovykh-dentalnykh-implantatov
24. Carreño Carreño J., Aguilar-Salvatierra A., Gómez-Moreno G., García Carreño E.M., Menéndez López-Mateos M.L., Perrotti V., Piattelli A., Calvo-Guirado J.L., Menéndez-Núñez M. Update of Surgical Techniques for Maxillary Sinus Augmentation: A Systematic Literature Review // Implant Dent. – 2016;25(6):839-844. doi: 10.1097/ID.0000000000000467.
25. Barylyak A.Y., Uhryn M.M., Got S.-R.R. Leczenie periimplantitis przy uzyciu lasera Er:YAG w polanczeniu z terapia fotodynamiczna. W: 2. Kongres Polskiego Towarzystwa Stomatologii Laserowej. 2017:7-8. https://elibrary.ru/item.asp?id=46113079
26. Chappuis V., Cavusoglu Y., Gruber R., Kuchler U., Buser D., Bosshardt D.D. Osseointegration of Zirconia in the Presence of Multinucleated Giant Cells // Clin Implant Dent Relat Res. – 2016;18(4):686-698. doi: 10.1111/cid.12375.
27. Cionca N., Hashim D., Cancela J., Giannopoulou C., Mombelli A. Pro-inflammatory cytokines at zirconia implants and teeth. A cross-sectional assessment // Clin Oral Investig. – 2016;20(8):2285-2291. doi: 10.1007/s00784-016-1729-z.
28. Cionca N., Hashim D., Mombelli A. Zirconia dental implants: where are we now, and where are we heading? // Periodontol 2000. – 2017;73(1):241-258. doi: 10.1111/prd.12180.
29. Got S.-R.R., Ugryn M.M., Bondarczuk O.L. Porownawcza ocean zastosowania przy protezowaniu na implantach przyczolkow tytanowych i z tlenku cyrkonu // Magazyn Stomatologiczny. – 2018;(12):40-44. doi:10.1111/prd.12185.
30. Grenade C., De Pauw-Gillet M.C., Pirard C., Bertrand V., Charlier C., Vanheusden A., Mainjot A. Biocompatibility of polymer-infiltrated-ceramic-network (PICN) materials with Human Gingival Keratinocytes (HGKs) // Dent Mater. – 2017;33(3):333-343. doi: 10.1016/j.dental.2017.01.001.
31. Jank S., Hochgatterer G. Success Rate of Two-Piece Zirconia Implants: A Retrospective Statistical Analysis // Implant Dent. – 2016;25(2):193-198. doi: 10.1097/ID.0000000000000365.
32. Kim G.O., Choi Y.S., Bae C.H., Song S.Y., Kim Y.D. Effect of titanium dioxide nanoparticles (TiO2 NPs) on the expression of mucin genes in human airway epithelial cells // Inhal Toxicol. – 2017;29(1):1-9. doi: 10.1080/08958378.2016.1267282.
33. Kim K.T., Eo M.Y., Nguyen T.T.H., Kim S.M. General review of titanium toxicity // Int J Implant Dent. – 2019;5(1):10. doi: 10.1186/s40729-019-0162-x.
34. Kohal R.J., Spies B.C., Bauer A., Butz F. One-piece zirconia oral implants for single-tooth replacement: Three-year results from a long-term prospective cohort study // J Clin Periodontol. – 2018;45(1):114-124. doi: 10.1111/jcpe.12815. Epub 2017 Nov 28. PMID: 28902420.
35. Mansoor Al-Taee M.J., Turke A.M., Al-Ethawi R.N,. Jabbar A.L. The effect of gold nanoparticles in growth and biofilm formation of methecillin resistant Staphylococcus aureus MRSA isolated from various clinical cases // Plant Archives. – 2018;18(1):601-608. doi: 10.5037/jomr.2021.12401.
36. Nishihara H., Haro Adanez M., Att W. Current status of zirconia implants in dentistry: preclinical tests // J Prosthodont Res. – 2019;63(1):1-14. doi: 10.1016/j.jpor.2018.07.006.
37. Osman R., Swain M. A Critical Review of Dental Implant Materials with an Emphasis on Titanium versus Zirconia // Materials. – 2015;8(3):932. doi: 10.3390/ma8030932.
38. Pieralli S., Kohal R.J., Jung R.E., Vach K., Spies B.C. Clinical Outcomes of Zirconia Dental Implants // J Dent Res. – 2017;96(1):38-46. doi: 10.1177/0022034516664043.
39. Pieralli S., Kohal R.J., Lopez Hernandez E., Doerken S., Spies B.C. Osseointegration of zirconia dental implants in animal investigations: A systematic review and meta-analysis // Dental Materials. – 2018;34(2):171-182. doi: 10.1016/j.dental.2017.10.008.
40. Polonskiy V.I., Asanova A.A. Assessment of titanium dioxide nanoparticle effects on living organisms // Reserch Gate. – 2018. doi: 10.25750/1995-4301-2018-3-005-011.
41. Roehling S., Astasov-Frauenhoffer M., Hauser-Gerspach I., Braissant O., Woelfler H., Waltimo T. In vitro biofilm formation on titanium and zirconia implant surfaces // J Periodontol. – 2017;88(3):298-307. doi: 10.1902/jop.2016.160245.
42. Safioti L.M., Kotsakis G.A., Pozhitkov A.E., Chung W.O., Daubert D.M. Increased levels of dissolved titanium are associated with peri-implantitis – a cross-sectional study // J Periodontol. – 2017;88:436-442. doi: 10.1038/sj.bdj.2017.669
43. Sivaraman K., Chopra A., Narayan A.I., Balakrishnan D. Is zirconia a viable alternative to titanium for oral implant? A critical review // J Prosthodont Res. – 2018;62(2):121-133. doi: 10.1016/j.jpor.2017.07.003.
44. Suárez-López Del Amo F., Rudek I., Wagner V.P., Martins M.D., O'Valle F., Galindo-Moreno P., Giannobile W.V., Wang H.L., Castilho R.M. Titanium Activates the DNA Damage Response Pathway in Oral Epithelial Cells: A Pilot Study // Int J Oral Maxillofac Implants. – 2017;32(6):1413-1420. doi: 10.11607/jomi.6077.
45. Thoma D.S., Gamper F.B., Sapata V.M., Voce G., Hammerle C.H.F., Sailer I. Spectrophotometric analysis of fluorescent zirconia abutments compared to “conventional” zirconia abutments: A within subject controlled clinical trial // Clin Implant Dent Relat Res. – 2017;19(4):760-766. doi: 10.1111/cid.12488.
46. Valentini X., Denefburg R., Patchi P. Morphological changes caused by exposure to TiO 2 nanoparticles in cultures of primary cortical neurons and in the rat brain // Toxicol Rep. – 2018;5:878-889. doi: 10.1002/cre2.582.
47. World health statistics 2021: monitoring health for the SDGs, sustainable development goals. Geneva : World Health Organization. 2021. Licence: CC BY-NC-SA 3.0 IGO. https://apps.who.int/iris/handle/10665/342703
