Russian Federation
The paper presents data reflecting the characteristics of drugs - xanthine derivatives. The breadth of pharmacological activity of xanthine compounds along with their safety has been established. The main directions of application of these drugs in the treatment of various diseases are shown. The main directions in the field of synthesis of new xanthine derivatives have been established, which can be used as effective drugs with various pharmacological effects.
xanthine derivatives, pharmacological activity
1. Antonov A.K., Bocharova O.A., Belousov A.V., Cymbal M.V., Grechko A.T. Primenenie adaptogenov v onkologii // Vestnik sluzhby krovi Rossii. 2011. № 2. S. 23-26.
2. Sambukova T.V., Ovchinnikov B.V., Ganapol'skiy V.P., Yatmanov A.N., Shabanov P.D. Perspektivy ispol'zovaniya fitopreparatov v sovremennoy farmakologii // Obzory po klinicheskoy farmakologii i lekarstvennoy terapii. 2017. T. 15, № 2. S. 56-63.
3. Sepiashvili R.I. Ot immunoterapii k personalizirovannoy targetnoy immunomoduliruyuschey terapii i immunoreabilitacii // Allergologiya i immunologiya. 2015. T. 16, № 4. S. 323-327.
4. Shur Yu. V., Shur V. Yu., Samotrueva M. A. Nekotorye mehanizmy immunotropnogo i adaptogennogo deystviya fitopreparatov // Obzory po klinicheskoy farmakologii i lekarstvennoy terapii. 2019. T. 17, № 4. S. 19-29.
5. Agarie S., Kawaguchi A., Kodera A., Sunagawa H., Kojima H., Nose A., Nakahara T. Potential of the common ice plant, Mesembryanthemum crystallinum as a new high-functional food as evaluated by polyol accumulation // Plant Production Science. 2009. Vol. 12. P. 37-46.
6. Bouftira I., Chedly A., Souad S. Antioxidant and Antibacterial Properties of Mesembryanthemum crystallinum and Carpobrotus edulis Extracts // Advances in Chemical Engineering and Science. 2012. Vol. 3. P.1-7.
7. Bouftira I., Abdelly C., Sfar S. Characterization of cosmetic cream with Mesembryanthemum crystallinum plant extract: influence of formulation composition on physical stability and anti-oxidant activity // International Journal of Cosmetic Science. 2008. Vol. 30. P. 443-452.
8. Kang M.J., Kim J.I., Yoon S.Y., Kim J.I.C., Cha I.J. Pinitol from soybeans reduces postprandial blood glucose in patients with type 2 diabetes mellitus // Journal of Medicinal Food. 2006. Vol. 9. P.182-186.
9. LeeS.Y., Choi H.D., Yu S.N., Kim S.H., Park S.K., Ahh S.C. Biological Activities of Mesembryanthemum crystallinum (Ice plant) Extract Ice plant (Mesembryanthemum crystallinum) // Journal of Life Science. 2015. Vol. 25. P. 638-645. 1
10. Loewus F.A., Murthy P.P.N. Myo-inositol metabolism in plants // Plant Science. 2000. Vol. 150. P.1-19.
11. Zhang C., Wu W., Xin X., Li X., Liu D. Extract of ice plant (Mesembryanthemum crystallinum) ameliorates hyperglycemia and modulates the gut microbiota composition in type 2 diabetic Goto-Kakizaki rats // Food & Function. 2019. Vol. 10. P. 3252-3261.
12. Dospehov B.A. Metodika polevogo opyta (s osnovami statisticheskoy obrabotki rezul'tatov issledovaniy), 5 izd., pererab. i dop. M.: Agropromizdat, 1985. 351 s.
13. Provedenie polevyh opytov s lekarstvennymi kul'turami / Pod red. Hotina A.A. Lekarstvennoe rastenievodstvo: Obzornaya informaciya. M.: CBNTImedprom, 1981. Vyp. 1. 55 s.
14. Gosudarstvennaya farmakopeya Rossiyskoy Federacii. XIII izdanie. Tom IV. Dostupno po: http://pharmacopoeia.ru/gosudarstvennaya-farmakopeya-xiii-online-gf-13-online
