The article presents the results of pharmacoepidemiological study, conducted with the aim of studying the peculiarities of antihypertensive therapy in patients with arterial hypertension (AH), and chronic obstructive pulmonary isease (COPD) in the Republic North Ossetia-Alania. Retrospective descriptive study according to the medical records of patients (n=568) of all outpatient clinics of the republic was performed. According to the obtained data, recommended by the doctors, the therapy does not correspond with the modern clinical recommendations on the majority of cases. The main lacks of the AH and COPD patients’ treatment are inadequate choice of the antihypertensive preparations for the start therapy, unfoundedly often use of monotherapy, non-rational combination of the medicinal drags, that leads to the absence of the carried out therapy effect in majority of patients.
arterial hypertension, chronic obstructive pulmonary disease, pharmacoepidemiology
1. Adasheva T. V. i dr. Antigipertenzivnaya terapiya u bol´nykh s khronicheskoy obstruktivnoy bolezn´yu legkikh: preimushchestva antagonistov kal´tsiya. Ratsional´naya farmakoterapiya v kardiologii, 2008. № 5.S. 39–45.
2. Global´naya strategiya diagnostiki, lecheniya i profilaktiki khronicheskoy obstruktivnoy bolezni legkikh (peresmotr 2011 g.); per. s angl. / pod red. A. S. Belevskogo. M.: Rossiyskoy respiratornoe obshchestvo, 2012. 80 s.
3. Zodionchenko V. S. i dr. Kliniko-funktsional´nye osobennosti arterial´noy gipertonii u bol´nykh khronicheskimi obstruktivnymi boleznyami legkikh. RMZh, 2003. № 9. S. 535–538.
4. Kanukova F. U., Astakhova Z. T. Effektivnost´ i bezopasnost´ kombinirovannoy antigipertenzivnoy terapii u bol´nykh stabil´noy arterial´noy gipertenziey. VMBV, 2010. № 10. Vyp. 17. S. 80–86.
5. Ovcharenko S. I., Nersesyan Z. I. Khronicheskaya obstruktivnaya bolezn´ legkikh i arterial´naya gipertoniya (obzor literatury). Consilium Medicum, 2012. № 11. S. 51–55.
6. Rossiyskoe meditsinskoe obshchestvo po arterial´noy gipertonii (RMOAG), Vserossiyskoe nauchnoe obshchestvo kardiologov (VNOK). Diagnostika i lechenie arterial´noy gipertenzii. Rossiyskie rekomendatsii (chetvertyy peresmotr), 2010.
7. Sidorenkova N. B., Manukyan A. V. Farmakoepidemiologiya arterial´noy gipertenzii. Remedium, 2009. № 6–7. S. 14–16.
8. Chazova I. E. i dr. Effektivnost´ antigipertenzivnoy terapii u bol´nykh arterial´noy gipertoniey v zavisimosti ot riska serdechno-sosudistykh oslozhneniy. Kardiovask. ter. i profilak., 2008. № 7 (2).S. 29–32.
9. Chuchalin A. G. Printsipy vedeniya patsientov s khronicheskimi obstruktivnymi boleznyami legkikh i soputstvuyushchimi kardiologicheskimi zabolevaniyami. Consilium Medicum, 2007. Ekstravypusk. S. 2–3.