employee
Tyumen', Tyumen, Russian Federation
employee from 01.01.2008 until now
Tyumen', Russian Federation
employee
Tyumen', Tyumen, Russian Federation
employee
Tyumen', Tyumen, Russian Federation
employee
Tyumen', Tyumen, Russian Federation
Methodology. 48 somatically healthy patients of both gender in age from 25 up to 45 was examined, that included questioning, examination, index estimation of the state of fabrics of paradontium, doppler ultrasound of vessels of paradontium with the use of device of "Minimax-Doppler-K" NB model with the sensor 20 Mhz. Linear speed of blood stream, volume speed of blood stream were defined. Patients were divided into 3 groups: 1 - basic group (n=22) are patients with chronic catarrhal gingivitis where the standard treatment was complemented by application of injections of gel, containing 1 % of hyaluronic acid and 0,015 % of hydrophilic polysaccharide of AGEG, under a mucous membrane on a mucogingival fold; 2 is a control group (n=16) patients with chronic catarrhal gingivitis and the standard treatment (in accordance with clinical recommendations) was complemented; 3 group are people with a clinically healthy paradontium (n=10). Dynamic estimation of efficiency of treatment was conducted on the 2 day and 7th day, 14th day, in 1 month, 3 months.Results. There was a stable reduction of PMA index in a basic group, that shows the efficiency of treatment and remission in the period of 3 months observation. More low level of PBI and PI (p<0,05) indexes was determined statistically meaningfully in a basic group, according to the results of 12 weeks of supervision.. Results. The indexes of hemodynamics had more obvious tendency to approach descriptions of intact paradontium.
gingivitis, pathogenetic therapy of inflammatory periodontal diseases, hyaluronic acid, sodium hyaluronate, microcirculation
1. Krechina, E. K., Zorina, O. A., Molchanov, A. M., Shilov, A. M. (2016). Narusheniye mikrotsirkulyatsii v tkanyakh parodonta u patsiyentov s khronicheskim generalizovannym parodontitom v sochetanii s metabolicheskim sindromom [Microcirculation impairment in periodontal tissues in patients with chronic generalized periodontitis combined with metabolic syndrome]. Stomatologiya [Dentistry], 95 (1), 2730. (InRuss.)
2. Kuz'mina, EH. M., Kuz'mina, I. N., Petrina, E. S., ed. Yanushevicha, O. O. (2009). Stomatologicheskaya zabolevayemost' naseleniya Rossii. Sostoyaniye tkaney parodonta i slizistoy obolochki rta [Dental morbidity in Russia. Condition of periodontal tissues and oral mucosa]. Moscow, 236. (In Russ.).
3. Miroshnichenko, V. V., Nagaeva, M. O., Marenova, O. E., Orlova, E. S. (2018). Sravnitel'nyy analiz effektivnosti kompleksnogo lecheniya patsiyentov s khronicheskim kataral'nym gingivitom na osnovanii indeksnoy otsenki pokazateley gemodinamiki parodonta [Comparative analysis of complex treatment effectiveness for patients with chronic catarrhal gingivitis on the basis of index evaluation and periodontal hemodynamic indicators]. Meditsinskaya nauka i obrazovanie Urala [Medical science and education of the Urals], 94 (2), 10–14. (In Russ.)
4. Mitronin, A. B., Vavilova, T. P., Zhilkina, O. E., Ostrovskaya, I. G. (2011). Primeneniye gel'soderzhashchikh preparatov «Gialudent» v lechenii vospalitel'nykh zabolevaniy parodonta [Application gel of containing of preparations Gialudent in treatment of inflammatory diseases periodontitis]. «Cathedra». Stomatologicheskoe obrazovanie [“Cathedra”. Dental education], 35, 31–34. (InRuss.).
5. Nagaeva, M. O., Kuman, O. A., Lebedev, S. N. (2017). Ekspertnyy situatsionnyy analiz stomatologicheskoy zabolevayemosti naseleniya Tyumenskoy oblasti – osnova dlya razrabotki regional'noy programmy pervichnoy profilaktiki [Expert case study of tyumen region dental disease rate is the basis for regional program primary prevention development]. Problemy stomatologii [Problems of dentistry], 13, 4, 50–55. (In Russ.)
6. Orekhova, L. YU., Barmasheva, A. A., Musaeva, R.S. (2014). Primeneniye ul'trazvukovoy dopplerografii pri otsenke effektivnosti parodontologicheskogo lecheniya patsiyentov s sakharnym diabetom [The use of Doppler ultrasound in evaluating the efficacy of treatment of periodontal patients with diabetes mellitus]. Metodi issledovaniya microcirculacii v klinike : sbornik nauchnih trudov nauchno-praktichescoy konferencii [Methods for the study of microcirculation in the clinic: a collection of scientific works -practical conference], St. Petersburg : SP Minimax, 160–168. (In Russ.)
7. Orekhova, L. YU., Loboda, E. S., Yamanidze, N. A. (2018). Sovershenstvovaniye metodov diagnostiki i lecheniya vospalitel'nykh zabolevaniy parodonta s ispol'zovaniyem razlichnykh form preparatov ozona putem otsenki mikrotsirkulyatsii tkaney parodonta [Improving the methods for the diagnosis and treatment of periodontal inflammatory diseases using various forms of medical ozone, by evaluating the microcirculation of periodontal tissues]. Parodontologiya [Parodontologiya], 1 (86), 58–63. (In Russ.)
8. Orekhova, L. Yu., Loboda, E. S., Yamanidze, N. A., Galeeva, A. R. (2018). Primeneniye gialuronovoy kisloty v kompleksnom lechenii zabolevaniy parodonta [The use (application) of hyaluronic acid in complex treatment of periodontal diseases]. Parodontologiya [Parodontologiya], 3 (88), 148–153. (In Russ.)
9. Sokolova, I., Khlystun, N. (2015). Lechebnoye deystviye oral'nykh geley s gialuronovoy kislotoy i kvertsetinom na sostoyaniye polosti rta u bol'nykh gingivitom [Therapeutic action oral gel with hyaluronic acid and quercetin on the oral cavity for patients with gingivitis]. Nauka i Zdravoohranenie [Science and Public Health], (6), 110–123. (In Russ.)
10. Ushakov, R. V., Ushakov, A. R., D'yakonova, M. S. (2017). Primeneniye preparatov gialuronovoy kisloty Revident v khirurgicheskoy stomatologii [Application of hyaluronic acid preparations Revident in surgical dentistry]. Meditsinskij alfavit [Medical alphabet], 24 (321), 3, 47–50. (In Russ.)
11. Chaykovskaya, E. A., Parsagashvili, E. Z. (2011). Gialuronovaya kislota: biologicheskiy kontrol' nad vospaleniyem i ranozazhivleniyem [Hyaluronic acid: biological control over inflammation and wound healing]. In"yektsionnyye metody v kosmetologii [Injection methods in cosmetology], (4), 20–29. (In Russ.)
12. Aimetti, M., Perotto, S., Castiglione, S et al. (2015). Prevalence of periodontitis in an adult population from anurban area in North Italy: findings from a cross-sectional population-based epidemiological survey. Journal of clinical periodontology, 42 (7), 622–631.
13. Bevilacqua, L., Eriani, J., Serroni, I., Liani, G., Borelli, V., Castronovo, G., Di Lenarda, R. (2012). Effectiveness of adjunctive subgingival administration of amino acids and so-dium hyaluronate gel on clinical and immunological parameters in the treatment of chronic periodontitis. Ann Stomatol (Roma), 3 (2), 75–81.
14. Casale, M., Moffa, A., Vella, P., Sabatino, L., Capuano, F., Salvinelli, B., Lopez, M. A., Carinci, F., Salvinelli, F. (2016). Hyaluronic acid: Perspectives in dentistry. A systematic review. Int J Immunopathol Pharmacol, 29 (4), 572–582.
15. Dahiya, P., Kamal, R. (2013). Hyaluronic acid: a boon in periodontal therapy. N. Am. J. Med. Sci, 5 (5), 309–315.
16. Eke, P. I., Dye, B. A., Wei, L., Thornton-Evans, G. O., Genco, R. J. (2012). Prevalence of periodontitis in adults in the united states: 2009 and 2010. J. Dent. Res, 91, 914–920.
17. Fawzy El-Sayed, K. M., Dahaba, M. A., Aboul-Ela, S., Darhous, M. S. (2012). Local application of hyaluronan gel in conjunction with periodontal surgery: a randomized con-trolled trial. Clin Oral Investig, 16 (4), 1229–1236.
18. Gontiya, G., Galgali, S. R. (2012). Effect of hyaluronan on periodontitis: A clinical and his-tological study. J Indian Soc Periodontol, 16 (2), 184–192
19. Johannsen, A., Tellefsen, M., Wikesjö, U., Johannsen, G. (2009). Local delivery of hyaluronan as an adjunct to scaling and root planing in the treatment of chronic periodontitis. J Periodontol, 80 (9), 1493–1497.
20. Mesa, F. L., Aneiros, J., Cabrera, A., Bravo, M., Caballero, T., Revelles, F., del Moral, R. G., O'Valle, F. (2002). Antiproliferative effect of topic hyaluronic acid gel. Study in gingival biopsies of patients with periodontal disease. Histol Histopathol, 17 (3), 747–753.
21. Necas, J., Bartosikova, L., Brauner, P. (2008). Hyaluronic acid (hyaluronan): review article. Veterinarni Medicina, 53 (8), 397–411.
22. Pilloni, A., Annibali, S., Dominici, F., Di Paolo, C., Papa, M., Cassini, M. A., Polimeni, A. (2011). Evaluation of the efficacy of an hyaluronic acid-based biogel on periodontal clin-ical parameters. A randomized-controlled clinical pilot study. Ann Stomatol (Roma), 2 (3-4), 3–9.
23. Rajan, P., Baramappa, R., Rao, N. M., Pavaluri, A. K., Rahaman, S. M. (2014). Hyaluronic Acid as an adjunct to scaling and root planing in chronic periodontitis. A random-ized clinical trail. J Clin Diagn Res, 8 (12), 11–14.
24. Sharma, V., Gupta, R., Dahiya, P., Kumar, M. (2016). Comparative evaluation of coenzyme Q10-based gel and 0.8% hyaluronic acid gel in treatment of chronic periodontitis. J Indian Soc Periodontol, 20 (4), 374–380.
25. Xu, Y., Frentzen, M., Jerve-Storm, P. M. (2004). Clinical study of hyaluronic acid in the treatment of chronic periodontitis. Hua Xi Kou Qiang Yi Xue Za Zhi, 22 (1), 32–34.
