The prevalence of opioid dependence among the able-bodied population is an important medical and social problem. Methylenetetrahydrofolate reductase (MTHFR) plays a key role in the metabolism of narcotic drugs. A decrease in the enzyme activity in polymorphic variants of the gene encoding it is associated with a decrease in the immunity of opioid addiction patients.
Opioids, apoptosis, lymphocyte atypical form, MTHFR
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