The paper presents the results of the preimplantation genetic testing for a couple in which both spouses are carriers of balanced autosomal translocations. The chromosome segregation pattern and individual characteristics of quadrivalents for both rearrangements were determined, and the risk of reproductive problems in a offspring who inherited a maternal translocation was assessed.
autosomal reciprocal translocations, segregation pattern, terminal breakpoints, quadrivalent asymmetry, centric and translocated segments
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